NCT06477445

Brief Summary

The goal of this clinical trial is to learn if visual feedback balance training system combined with repetitive facilitative exercise (RFE) work to treat stroke in adults. The main questions it aims to answer are: Does visual feedback balance training system combined with RFE reduce the fall risk of participants? Can the combination of intelligent rehabilitation robot training system and RFE achieve better effects? Researchers will compare 3 groups (RFE, visual feedback balance training system under RFE, and conventional therapy) to see if visual feedback balance training system and RFE works to treat stroke. Participants will: Receive treatment for 4 weeks Receive scale and instrument testing before and after treatment

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P50-P75 for not_applicable stroke

Timeline
Completed

Started Jul 2024

Shorter than P25 for not_applicable stroke

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 21, 2024

Completed
6 days until next milestone

First Posted

Study publicly available on registry

June 27, 2024

Completed
4 days until next milestone

Study Start

First participant enrolled

July 1, 2024

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2024

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2024

Completed
Last Updated

June 27, 2024

Status Verified

June 1, 2024

Enrollment Period

2 months

First QC Date

June 21, 2024

Last Update Submit

June 21, 2024

Conditions

Outcome Measures

Primary Outcomes (4)

  • time up and go test (TUG)

    From enrollment to the end of treatment at 4 weeks

  • 10-meter walk test (10-MWT)

    From enrollment to the end of treatment at 4 weeks

  • Center of gravity loss index

    Use the Libra parameters evaluation system included with visual feedback balance training system

    From enrollment to the end of treatment at 4 weeks

  • Deviation of bilateral center of gravity movement area

    Use the Libra parameters evaluation system included with visual feedback balance training system

    From enrollment to the end of treatment at 4 weeks

Secondary Outcomes (3)

  • functional ambulation category scale (FAC)

    From enrollment to the end of treatment at 4 weeks

  • Fugl-Meyer Assessment (FMA)

    From enrollment to the end of treatment at 4 weeks

  • Berg balance scale (BBS)

    From enrollment to the end of treatment at 4 weeks

Study Arms (3)

Combination group

EXPERIMENTAL

Visual feedback balance training system combined with RFE

Device: Visual feedback balance training systemOther: repetitive facilitative exercise

RFE group

ACTIVE COMPARATOR

Repetitive facilitative exercise (RFE)

Other: repetitive facilitative exercise

CT group

ACTIVE COMPARATOR

Conventional therapy (CT)

Other: conventional therapy

Interventions

Using an visual feedback balance training system to provide a dynamic balance training platform for patients to perform balance training based on visual feedback.

Combination group

Repetitive facilitative exercise (RFE) is a new technology that combines multiple sensory stimuli and achieves facilitation and reinforcement of the reconstruction of paralyzed neural pathways through repeated and extensive directional exercise.

Combination groupRFE group

Basic training, including passive joint movement and activities of daily living exercise.

CT group

Eligibility Criteria

Age18 Years - 74 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • patients (18 to 74 years old) who suffered a first or second unilateral stroke
  • chronic stroke (over 6 months from the onset)
  • moderate or higher risk of falls (TUG \> 15s, or 10-MWT ≤ 0.8m/s)
  • ability to understand and follow simple directions

You may not qualify if:

  • pregnant or lactating
  • lower extremity contracture, pain, or trauma
  • perceptual, apraxic, or cognitive deficits that lead to inability to follow verbal instructions
  • unable to maintain standing posture
  • cerebellar lesion
  • clinically unstable medical disorders
  • inability to provide informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, CARE PROVIDER, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
therapist-in-charge

Study Record Dates

First Submitted

June 21, 2024

First Posted

June 27, 2024

Study Start

July 1, 2024

Primary Completion

September 1, 2024

Study Completion

October 1, 2024

Last Updated

June 27, 2024

Record last verified: 2024-06