Respiratory Muscle Training and Quality of Life in Hemodialysis Patients

NCT07183696 | Recruiting DMC

• 1 other identifier: P.T.REC/012/005826
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

This study investigates the effect of breath booster training on respiratory muscle strength and quality of life in patients undergoing hemodialysis. It aims to determine whether targeted respiratory training can improve pulmonary function, enhance physical performance, and positively impact overall well-being in this population.

Conditions

Hemodialysis

Outcome Measures

Primary Outcomes (2)

• Respiratory Muscle Strength measured using Respiratory Pressure Manometers

  Outcomes include maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP), recorded in cmH₂O. Higher values indicate greater respiratory muscle strength.

  6 weeks

• Health-Related Quality of Life assessed by the 36-Item Short Form Health Survey

  It includes eight domains (physical functioning, role limitations, bodily pain, general health, vitality, social functioning, role-emotional, and mental health). Scores are transformed to a 0-100 scale, where 0 = worst health and 100 = best health. Higher scores indicate better health-related quality of life.

  for 6 weeks

Study Arms (2)

Placebo

PLACEBO COMPARATOR

will receive respiratory physical therapy sessions in the form of breathing exercises, chest percussion, and vibration 3 times per week during dialysis sessions for 6 weeks

Other: breathing exercises

Intervention Group

EXPERIMENTAL

will receive respiratory physicaltherapy sessions in the form of breathing exercises, chest percussion, and vibration 3 times per week during dialysis sessions for 6 weeks and training on the breath booster device at the same session

Other: breathing exercises

Interventions

breathing exercises OTHER

* breathing exercises as needed 3 times per week during dialysis sessions. * chest percussion as needed 3 times per week during dialysis sessions. * vibration as needed 3 times per week during dialysis sessions.

Also known as: chest percussion, vibration

Intervention Group; Placebo

Eligibility Criteria

• Age: 50 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Fifty patients will be included in this study.
• Their ages will range from 50 to 60 years.
• Patients with end-stage renal disease (grade 5) receiving hemodialysis.
• Patients on hemodialysis for around 1 to 3 years.
• They will be able to follow instructions during evaluation and treatment.

You may not qualify if:

• Diabetes Mellitus,
• Morbid obesity with a BMI of more than 35 kg/m2.
• Hearing or visual impairments.
• Any severe chest diseases like COPD.
• Certain contraindications for the use of the Breath Booster. Individuals with severe respiratory conditions such as unstable asthma, or emphysema, or those who have recently undergone lung surgery
• Uncontrolled seizures.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Faculty of physical therapy cairo university

Giza, Egypt

RECRUITING

MeSH Terms

Interventions

Breathing Exercises; Vibration

Intervention Hierarchy (Ancestors)

Mind-Body Therapies; Complementary Therapies; Therapeutics; Exercise Movement Techniques; Physical Therapy Modalities; Mechanical Phenomena; Physical Phenomena

Central Study Contacts

Sameh Eldaly Sameh Eldaly

CONTACT

+201554076441; info@sameheldaly.online

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: director of scientific research committee

Study Record Dates

• First Submitted: September 11, 2025
• First Posted: September 19, 2025
• Study Start: October 1, 2024
• Primary Completion: October 1, 2025
• Study Completion: October 1, 2025
• Last Updated: September 19, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)