NCT06467877

Brief Summary

Patients with hypercalcemia were identified in the patient population of a German emergency department during a 11 year time period and studied regarding reproducibility of elevated calcium values, causes of hypercalcemia, symptoms. acute renal injury, mortality and treatment response.

Trial Health

55
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2010

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2010

Completed
11.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2021

Completed
3.2 years until next milestone

First Submitted

Initial submission to the registry

June 14, 2024

Completed
7 days until next milestone

First Posted

Study publicly available on registry

June 21, 2024

Completed
1.5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2025

Completed
Last Updated

December 9, 2024

Status Verified

December 1, 2024

Enrollment Period

11.3 years

First QC Date

June 14, 2024

Last Update Submit

December 4, 2024

Conditions

Hypercalcemia

Keywords

hypercalcemiacalciumemergency roommortality

Outcome Measures

Primary Outcomes (1)

  • Development of total calcium values

    Overview of total calcium values within 5 days

    5 days after enrollment

Secondary Outcomes (3)

  • Reproducibility of elevated calcium values

    5 days after enrollment

  • Correlation creatinine calcium

    5 days after enrollment

  • Mortality

    5 days after enrollment

Study Arms (1)

Retrospective Chart Review

Group includes patient with hypercalcemia ≥2.65 mmol/l, who reported to the emergency room of a tertiary hospital

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients reporting to the Emergency Room of the University Hospital Cologne and recieved a determination of the total calcium level

You may qualify if:

  • Age \> 18 years
  • Total calcium ≥ 2.65 mmol/l
  • Female and male

You may not qualify if:

  • Age \< 18 years
  • Total calcium \< 2.65 mmol/

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department II of Internal Medicine,University of Cologne

Cologne, 50937, Germany

Location

MeSH Terms

Conditions

HypercalcemiaEmergencies

Condition Hierarchy (Ancestors)

Calcium Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesWater-Electrolyte ImbalanceDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Volker Burst, MD

    University Hospital of Cologne

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Prof. Dr. med.

Study Record Dates

First Submitted

June 14, 2024

First Posted

June 21, 2024

Study Start

January 1, 2010

Primary Completion

March 31, 2021

Study Completion

December 31, 2025

Last Updated

December 9, 2024

Record last verified: 2024-12

Data Sharing

IPD Sharing
Will not share

Locations

DE(1)