Study of Ventilator Associated Event During Intensive Care After Resuscitated Cardiac Arrest.

NCT06466980 | Recruiting

• 1 other identifier: 2024/0009
• Study Type: observational
• Target: 150
• Locations: 1 country
• Sites: 1

Brief Summary

The aim is to describe the incidence, characteristics, risk factors and outcome of complications acquired under mechanical ventilation (called ventilator-associated events) according to the new CDC criteria, in a population of patients admitted in intensive care unit after cardiac arrest.

Conditions

Cardiac Arrest With Successful Resuscitation; Mechanical Ventilation

Keywords

Ventilator associated event; cardiac arrest; ventilator-acquired pneumonia; ventilator associated pneumonia

Outcome Measures

Primary Outcomes (1)

• number

  Incidence of ventilator associated event

  at day 28

Secondary Outcomes (4)

• Associated factors

  at day 28

• number of pneumonias

  at day 28

• time

  at day 28

• number of deaths

  at day 28

Interventions

Ventilator associated event OTHER

Measure of incidence of Ventilator associated event

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patient admitted to intensive care unit after cardiac arrest at the South Francilien Hospital Center from January 2019 to December 2023

You may qualify if:

• Adult male or female
• Non-pregnant female
• Successfully resuscitated from cardiac arrest during primary care
• Invasive mechanical ventilation initiated during resuscitation and continued for at least 4 days
• No decision to limit life-sustaining therapies within 24 hours following admission to intensive care
• No requirement of arteriovenous circulatory support during intensive care management

You may not qualify if:

• \- patients who opposed to the use of their data

Sponsors & Collaborators

• Centre Hospitalier Sud Francilien: lead

Study Sites (1)

Centre Hospitalier Sud Francilien

Corbeil-Essonnes, 91106, France

RECRUITING

Related Publications (2)

• American Thoracic Society; Infectious Diseases Society of America. Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med. 2005 Feb 15;171(4):388-416. doi: 10.1164/rccm.200405-644ST. No abstract available.

  PMID: 15699079 BACKGROUND

• Perbet S, Mongardon N, Dumas F, Bruel C, Lemiale V, Mourvillier B, Carli P, Varenne O, Mira JP, Wolff M, Cariou A. Early-onset pneumonia after cardiac arrest: characteristics, risk factors and influence on prognosis. Am J Respir Crit Care Med. 2011 Nov 1;184(9):1048-54. doi: 10.1164/rccm.201102-0331OC.

  PMID: 21816940 BACKGROUND

MeSH Terms

Conditions

Heart Arrest; Pneumonia, Ventilator-Associated

Condition Hierarchy (Ancestors)

Heart Diseases; Cardiovascular Diseases; Healthcare-Associated Pneumonia; Cross Infection; Infections; Pneumonia; Respiratory Tract Infections; Lung Diseases; Respiratory Tract Diseases; Iatrogenic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Central Study Contacts

Fabrice COOK, MD

CONTACT

01 61 69 52 28; fabrice.cook@chsf.fr

Caroline TOURTE

CONTACT

01 61 69 31 50; caroline.tourte@chsf.fr

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 14, 2024
• First Posted: June 20, 2024
• Study Start: June 27, 2024
• Primary Completion: December 31, 2025
• Study Completion: December 31, 2025
• Last Updated: March 14, 2025

Record last verified: 2025-03

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)