NCT06465927

Brief Summary

Acute appendicitis with an appendicolith is one of the most common abdominal emergencies in elderly patients and is more likely to progress to gangrene and perforation. This study aimed to analyze the clinical data of patients over 80 years old who underwent emergency appendectomy for acute appendicitis, to explore the clinical significance of appendicoliths, and to improve treatment strategies.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
130

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jul 2024

Shorter than P25 for all trials

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 14, 2024

Completed
6 days until next milestone

First Posted

Study publicly available on registry

June 20, 2024

Completed
11 days until next milestone

Study Start

First participant enrolled

July 1, 2024

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 31, 2024

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2024

Completed
Last Updated

June 20, 2024

Status Verified

June 1, 2024

Enrollment Period

2 months

First QC Date

June 14, 2024

Last Update Submit

June 18, 2024

Conditions

Outcome Measures

Primary Outcomes (2)

  • Morbidity of elderly patients undergoing emergency appendectomy

    Morbidity of elderly acute appendicitis patients with an appendicolith who underwent emergency appendectomy

    January 01, 2024 to December 31, 2024.

  • Mortality of elderly patients undergoing emergency appendectomy

    Mortality of elderly acute appendicitis patients with an appendicolith who underwent emergency appendectomy

    January 01, 2024 to December 31, 2024.

Interventions

Clinical data of elderly acute appendicitis patients with an appendicolith who underwent emergency appendectomy were collected and analyzed.

Eligibility Criteria

Age80 Years - 100 Years
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)
Sampling MethodProbability Sample
Study Population

The patients over 80 years old who underwent emergency appendectomy for acute appendicitis at the Department of Emergency Surgery of Zhongshan Hospital, Fudan University, from January 2016 to March 2023.

You may qualify if:

  • Patients who aged 80 years or older, who received conservative treatment for less than 24 hours before surgery, who had no peri-appendiceal abscess larger than 2 cm in diameter on CT scan, who underwent emergency appendectomy, and who had postoperative pathological confirmation of acute appendicitis.

You may not qualify if:

  • Patients younger than 80 years, those with malignancies, and those with incomplete clinical or pathological records were excluded from the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 14, 2024

First Posted

June 20, 2024

Study Start

July 1, 2024

Primary Completion

August 31, 2024

Study Completion

December 31, 2024

Last Updated

June 20, 2024

Record last verified: 2024-06