NCT06458049

Brief Summary

SHAREonline is a study for young female cancer survivors that are experiencing changes in sexual health and function. The purpose of this research is to compare two brief interventions delivered by videoconference to learn if they help women effectively manage these changes and restore sexual health and functioning.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
84

participants targeted

Target at P50-P75 for not_applicable

Timeline
13mo left

Started Feb 2025

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress53%
Feb 2025May 2027

First Submitted

Initial submission to the registry

June 10, 2024

Completed
3 days until next milestone

First Posted

Study publicly available on registry

June 13, 2024

Completed
8 months until next milestone

Study Start

First participant enrolled

February 19, 2025

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 31, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 31, 2027

Last Updated

February 24, 2026

Status Verified

February 1, 2026

Enrollment Period

2.3 years

First QC Date

June 10, 2024

Last Update Submit

February 23, 2026

Conditions

Keywords

Cancer SurvivorshipSexual Function Disturbances

Outcome Measures

Primary Outcomes (1)

  • Change in Sexual Function

    The Female Sexual Function Index (FSFI Full Scale Score), is 19-item instrument which measures sexual function, including desire, orgasm, pain and satisfaction.

    Baseline to 2 months

Secondary Outcomes (10)

  • Change in Emotional Distress

    Baseline to 2 month

  • Change in Sexual Function

    Baseline to 4 months

  • Change in Emotional Distress

    Baseline to 4 months

  • Enrollment Rate

    Baseline to 1 month

  • Intervention Acceptability Rate

    Up to 1 month-post intervention

  • +5 more secondary outcomes

Other Outcomes (3)

  • Sexual Self-efficacy

    Baseline to 2 months

  • Sexual Self-efficacy

    Baseline to 4 months

  • Coaching Satisfaction Summary

    Up to 1 month post-coaching session

Study Arms (2)

SHAREonline

EXPERIMENTAL

Participants will receive: * One online group session structured around three 60-minute modules and creation of a personal action plan * Single Coaching phone call at one month * Questionnaires to complete at baseline, 2 and 4 Months

Behavioral: Group SessionBehavioral: Coaching Call

Individual Self Management

ACTIVE COMPARATOR

Brief individualized session with online and written materials and guidance. All Participants will complete study questionnaires at baseline, 2 months and 4 months post intervention

Behavioral: Educational Materials

Interventions

Group SessionBEHAVIORAL

On-line educational session-3 modules-1 hour each for a total of 3 hours

SHAREonline
Coaching CallBEHAVIORAL

Single Coaching phone call at one month

SHAREonline

Individual videoconference session in which participants will receive a pdf of the American Cancer Society booklet, 'Sex and the Adult Female with Cancer

Individual Self Management

Eligibility Criteria

Age19 Years - 49 Years
Sexfemale(Gender-based eligibility)
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may not qualify if:

  • Has never been sexually active
  • Any impairment (e.g., hearing, visual, cognitive) that interferes with the ability to complete all study procedures independently

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Dana Farber Cancer Institute

Boston, Massachusetts, 02215, United States

Location

MeSH Terms

Conditions

Sexual Dysfunctions, Psychological

Condition Hierarchy (Ancestors)

Mental Disorders

Study Officials

  • Sharon Bober, PhD

    Dana-Farber Cancer Institute

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

June 10, 2024

First Posted

June 13, 2024

Study Start

February 19, 2025

Primary Completion (Estimated)

May 31, 2027

Study Completion (Estimated)

May 31, 2027

Last Updated

February 24, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will share

The Dana-Farber / Harvard Cancer Center encourages and supports the responsible and ethical sharing of data from clinical trials. De-identified participant data from the final research dataset used in the published manuscript may only be shared under the terms of a Data Use Agreement. Requests may be directed to: \[contact information for Sponsor Investigator or designee\]. The protocol and statistical analysis plan will be made available on Clinicaltrials.gov only as required by federal regulation or as a condition of awards and agreements supporting the research.

Shared Documents
STUDY PROTOCOL, SAP
Time Frame
Data can be shared no earlier than 1 year following the date of publication
Access Criteria
Contact the Belfer Office for Dana-Farber Innovations (BODFI) at innovation@dfci.harvard.edu

Locations