Detection of Early Airway Obstruction in Patients with COPD Using RCexp
COPD TiCON
1 other identifier
observational
1,000
0 countries
N/A
Brief Summary
We hypothesize that Cexp during tidal and forced exhalation implemented to the routine spirometer may detect airway obstruction earlier than conventional spirometric indices such as FEV1 and FEV1/FVC.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2025
Longer than P75 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
June 6, 2024
CompletedFirst Posted
Study publicly available on registry
June 13, 2024
CompletedStudy Start
First participant enrolled
January 1, 2025
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 31, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
December 31, 2028
ExpectedJune 13, 2024
June 1, 2024
12 months
June 6, 2024
June 6, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Association of early airway obstruction and positivity of RCexp
research correlation of RCexp1, RCexp2, and RCexp3 with FEV1 and FEV1/FVC in patients with known COPD and its correlation with healthy controls
January 2025 - December 2028
Study Arms (1)
all patients undergoing routine spirometry
all patients undergoing routine spirometry and have GOLD or STAR negative criteria but positive RCexp
Eligibility Criteria
All patients that are subjected to routine spirometry
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Depta F, Euliano NR, Zdravkovic M, Torok P, Gentile MA. Time constant to determine PEEP levels in mechanically ventilated COVID-19 ARDS: a feasibility study. BMC Anesthesiol. 2022 Dec 13;22(1):387. doi: 10.1186/s12871-022-01935-8.
PMID: 36513978BACKGROUND
Biospecimen
venous blood
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- MD, PhD
Study Record Dates
First Submitted
June 6, 2024
First Posted
June 13, 2024
Study Start
January 1, 2025
Primary Completion
December 31, 2025
Study Completion (Estimated)
December 31, 2028
Last Updated
June 13, 2024
Record last verified: 2024-06