Egyptian Arthroplasty Surgeons' Antibiotics Usage Awareness

NCT06451224 | Completed

• 1 other identifier: 04-2024-300439
• Study Type: observational
• Target: 105
• Locations: 1 country
• Sites: 1

Brief Summary

Total hip arthroplasty (THA) and total knee arthroplasty (TKA) are procedures successfully applied to manage various end-stage chronic hip and knee diseases, such as osteoarthritis, rheumatoid arthritis, and femoral head avascular necrosis, as well as acute conditions, such as the neck of femur fractures, with excellent long-term functional outcomes. One of the devastating complications after such a procedure is periprosthetic joint infection (PJI). Various precautions are proposed to guard against such complications; one is the administration of perioperative antibiotics. However, injudicious or misuse of antibiotics could lead to the emergence of antimicrobial resistance, further complicating this matter. This is why various scientific and research organizations have proposed guidelines and a consensus for proper antibiotic use in perioperative THA and TKA surgery. Antibiotic prophylaxis during primary THA and TKA can reduce the risk of PJI and surgical site infections. However, there is a lack of consensus on the optimal dosages and duration of prophylaxis, and guidelines vary among institutions. Alternatives such as extended oral antibiotic prophylaxis and different antibiotic regimens are being explored. International research is needed to establish best practices and determine the potential risks of antibiotic prophylaxis during primary THA and TKA. Unfortunately, the investigators are unaware of such guidelines proposed by any Egyptian health authority to guide and control the proper utilization of antibiotics during orthoapedic practice in general and joint replacement surgeries (THA and TKA) in particular.

Conditions

Infections Joint Prosthetic

Outcome Measures

Primary Outcomes (1)

• To determine the type of antibiotics administration during primary total hip and knee arthroplasty

  The type of antibiotics will be determined as follows: the name of the antibiotic (brand or generic), and if single or dual antibiotics are used. These will be presented as numbers and percentages.

  2 months

Secondary Outcomes (3)

• To determine the dose of antibiotics administered during primary total hip and knee arthroplasty

  2 months

• To determine the timing of antibiotics administration during primary total hip and knee arthroplasty

  2 months

• To determine the length of antibiotics administration during primary total hip and knee arthroplasty

  2 months

Interventions

Questionnaire OTHER

Online Questionnaire

Eligibility Criteria

• Age: 25 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Active practicing Egyptian joint replacement surgeons

You may qualify if:

• All Egyptian registered members of the Egyptian Pelvis and Hip Society, practicing Egyptian joint replacement surgeons (performing surgeries as a leading surgeon) who are willing to participate

You may not qualify if:

• Members not listed in the E-mail directory of the society
• Surgeons refusing to participate
• Young surgeons who are not practicing independently

Sponsors & Collaborators

• South Valley University: lead
• Assiut University: collaborator

Study Sites (1)

Assuit Faculty of Medicine

Asyut, Asyut Governorate, Egypt

Location

MeSH Terms

Interventions

Surveys and Questionnaires

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Ahmed Abd El-Aal, MD

  Assiut University

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: May 23, 2024
• First Posted: June 11, 2024
• Study Start: June 15, 2024
• Primary Completion: August 30, 2024
• Study Completion: September 30, 2024
• Last Updated: October 16, 2024

Record last verified: 2024-10

Locations

EG (1)