NCT06450353

Brief Summary

To look at the effect of a recipient's ancestry and socio-economic status on their choice of bone marrow transplantation donor cells and their chance of receiving genetically similar (allogeneic) bone marrow cells versus cells that are not genetically similar (allograft).

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,200

participants targeted

Target at P75+ for all trials

Timeline
37mo left

Started May 2024

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress39%
May 2024Jun 2029

First Submitted

Initial submission to the registry

May 31, 2024

Completed
Same day until next milestone

Study Start

First participant enrolled

May 31, 2024

Completed
10 days until next milestone

First Posted

Study publicly available on registry

June 10, 2024

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2027

Expected
2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2029

Last Updated

January 14, 2026

Status Verified

January 1, 2026

Enrollment Period

3 years

First QC Date

May 31, 2024

Last Update Submit

January 13, 2026

Conditions

Allogeneic Transplantation

Outcome Measures

Primary Outcomes (1)

  • Patient Ancestry Questionnaire

    Through study completion; an average of 1 year.

Study Arms (1)

Prospective evaluation

Participants are expected to be in this research study for up to 2 years after the participants bone marrow transplantation. However, your active participation will only last 1 day, when you sign the consent form and complete a questionnaire about your demographic information and ancestry (family ethnicity). For the rest of the study, information about the participants medical history, choice of bone marrow donor, and health outcomes will be collected from your medical record.

Behavioral: Patient Ancestry Questionnaires

Interventions

Patient Ancestry QuestionnairesBEHAVIORAL

Participants will be asked to complete a demographics and ancestry questionnaire at the baseline visit before you and your doctor select bone marrow donation candidates.

Prospective evaluation

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

MD Anderson Cancer Center

You may qualify if:

  • ≥ 18 years of age.
  • Candidate for allogeneic transplantation

You may not qualify if:

  • \) Allogeneic stem cell transplantation not medically indicated.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

MD Anderson Cancer Center

Houston, Texas, 77030, United States

RECRUITING

Related Links

Study Officials

  • Warren Fingrut, MD

    M.D. Anderson Cancer Center

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Warren Fingrut, MD

CONTACT

(832) 387-8363wbfingrut@mdanderson.org

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 31, 2024

First Posted

June 10, 2024

Study Start

May 31, 2024

Primary Completion (Estimated)

June 1, 2027

Study Completion (Estimated)

June 1, 2029

Last Updated

January 14, 2026

Record last verified: 2026-01

Locations

US(1)