NCT06450067

Brief Summary

This clinical trial is a non-interventional, observational, multicenter, post-marketing real-world study to evaluate the efficacy and safety of Inaticabtagene Autoleucel Injection in Chinese adult patients with relapsed or refractory B-cell acute lymphoblastic leukemia.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
200

participants targeted

Target at P75+ for all trials

Timeline
38mo left

Started Jun 2024

Longer than P75 for all trials

Geographic Reach
1 country

10 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress38%
Jun 2024Jun 2029

First Submitted

Initial submission to the registry

June 3, 2024

Completed
2 days until next milestone

Study Start

First participant enrolled

June 5, 2024

Completed
5 days until next milestone

First Posted

Study publicly available on registry

June 10, 2024

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 5, 2026

Expected
3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 5, 2029

Last Updated

September 19, 2024

Status Verified

September 1, 2024

Enrollment Period

2 years

First QC Date

June 3, 2024

Last Update Submit

September 18, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • overall survival

    OS is defined as the time from the start date of Inaticabtagene Autoleucel Injection infusion to the date of death due to any cause.

    2 years

Study Arms (1)

Diagnosed relapsed or refractory B-cell acute lymphoblastic leukemia

Diagnosed relapsed or refractory B-cell acute lymphoblastic leukemia

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Diagnosed with adult relapsed or refractory B-cell acute lymphoblastic leukemia.

You may qualify if:

  • Age ≥ 18 years;
  • Diagnosed with relapsed or refractory B-cell acute lymphoblastic leukemia;
  • Patients deemed eligible for receiving commercial Inaticabtagene Autoleucel injection treatment as determined by the investigator;
  • Patients voluntarily participate in this study and sign an informed consent form. For patients lacking full legal capacity, informed consent must be obtained from their legal guardian

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (10)

Peking University People's Hospital

Beijing, Beijing Municipality, 100000, China

RECRUITING

Peking University Third Hospital

Beijing, Beijing Municipality, 100000, China

RECRUITING

Zhujiang Hospital of Southern Medical University

Guangzhou, Guangdong, China

RECRUITING

Henan Cancer Hospital Affiliated Cancer Hospital of Zhengzhou University

Zhengzhou, Henan, China

RECRUITING

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, China

RECRUITING

The Affiliated Hospital of Xuzhou Medical University

Xuzhou, Jiangsu, China

RECRUITING

Qilu Hospital of Shandong university

Jinan, Shandong, China

RECRUITING

Tongji Hospital of Tongji University

Shanghai, Shanghai Municipality, China

RECRUITING

West China School of Medicine/West China Hospital of Sichuan University

Chengdu, Sichuan, China

RECRUITING

Institute of Hematology & Blood Diseases Hospital

Tianjin, Tianjin Municipality, China

RECRUITING

MeSH Terms

Conditions

Burkitt Lymphoma

Condition Hierarchy (Ancestors)

Epstein-Barr Virus InfectionsHerpesviridae InfectionsDNA Virus InfectionsVirus DiseasesInfectionsTumor Virus InfectionsLymphoma, B-CellLymphoma, Non-HodgkinLymphomaNeoplasms by Histologic TypeNeoplasmsLymphoproliferative DisordersLymphatic DiseasesHemic and Lymphatic DiseasesImmunoproliferative DisordersImmune System Diseases

Study Officials

  • Jianxiang Wang, Dr.

    Institute of Hematology & Blood Diseases Hospital, China

    PRINCIPAL INVESTIGATOR
  • Aibin Liang, Dr.

    Tongji Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Qinghan Wang, master

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 3, 2024

First Posted

June 10, 2024

Study Start

June 5, 2024

Primary Completion (Estimated)

June 5, 2026

Study Completion (Estimated)

June 5, 2029

Last Updated

September 19, 2024

Record last verified: 2024-09

Data Sharing

IPD Sharing
Will not share

Locations