Key Insights

Highlights

Success Rate

83% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

2.2%

2 terminated out of 90 trials

Success Rate

83.3%

-3.2% vs benchmark

Late-Stage Pipeline

2%

2 trials in Phase 3/4

Results Transparency

50%

5 of 10 completed with results

Key Signals

5 with results83% success

Data Visualizations

Phase Distribution

86Total
Not Applicable (3)
Early P 1 (10)
P 1 (48)
P 2 (23)
P 3 (2)

Trial Status

Recruiting38
Unknown21
Completed10
Withdrawn7
Active Not Recruiting6
Not Yet Recruiting5

Trial Success Rate

83.3%

Benchmark: 86.5%

Based on 10 completed trials

Clinical Trials (90)

Showing 20 of 20 trials
NCT07570173Phase 2Not Yet RecruitingPrimary

A Clinical Trial of MK-1045 in People With B-cell Acute Lymphoblastic Leukemia (MK-1045-005)

NCT07153796Phase 2RecruitingPrimary

A Phase 2 Study to Assess the Safety and Efficacy of Subcutaneous Blinatumomab in Combination With Low Intensity Chemotherapy in Older Patients With Newly Diagnosed B-cell Acute Lymphoblastic Leukemia

NCT04094311Phase 3RecruitingPrimary

Study of Out of Specification for Tisagenlecleucel

NCT05020678Phase 1Active Not Recruiting

NKX019, Intravenous Allogeneic Chimeric Antigen Receptor Natural Killer Cells (CAR NK), in Adults With B-cell Cancers

NCT04544592Phase 1RecruitingPrimary

UCD19 CarT in Treatment of Pediatric B-ALL and B-NHL

NCT07313852Phase 1Not Yet RecruitingPrimary

A Study of Inotuzumab and Blinatumomab in People With B-cell Acute Lymphoblastic Leukemia

NCT03876769Phase 2Active Not RecruitingPrimary

Study of Efficacy and Safety of Tisagenlecleucel in HR B-ALL EOC MRD Positive Patients

NCT06395103Phase 1RecruitingPrimary

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

NCT07223021Phase 3RecruitingPrimary

A Study of Fludarabine Dosing in Children and Young Adults With B-cell Acute Lymphoblastic Leukemia

NCT06533579Phase 1RecruitingPrimary

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

NCT05674175Phase 1RecruitingPrimary

Co-administration of CART22-65s and huCART19 for B-ALL

NCT06343090Not ApplicableRecruitingPrimary

Clinical Trial of CD19 and CD22 CAR Sequential Therapy Versus Single CD19 CAR Bridging to HSCT for r/r B-ALL Patients

NCT06326008Phase 1RecruitingPrimary

Safety, Tolerability, and Pharmacokinetics of Donor-derived CD19 CAR Therapy Bridged Allo-HSCT and Sequential Donor-derived CD22 CAR Therapy for r/r B-ALL: a Clinical Trial

NCT07422337Recruiting

A Multi-site Study to Evaluate the Persistence of Protective Immunity to Routine Childhood Vaccinations in Participants With B-ALL/Ly Who Have Received Blinatumomab

NCT06389305Not ApplicableRecruitingPrimary

CIK Cell Therapy for Relapsed or Refractory Acute B-Lymphoblastic Leukemia: Prognostic Impact on Patients With Early CAR-T Cell Dysfunction

NCT07429461Early Phase 1RecruitingPrimary

Clinical Study of SYNCAR-100 in the Treatment of Relapsed/Refractory Acute B-Lymphoblastic Leukemia

NCT06863259Phase 1RecruitingPrimary

Study of Inotuzumab Ozogamicin, Venetoclax, and Dexamethasone for Relapsed B-cell ALL

NCT06580301Phase 1RecruitingPrimary

Study of YK012 in B-cell Acute Lymphoblastic Leukemia

NCT05460533Phase 2Active Not RecruitingPrimary

A Second Infusion (Early Reinfusion) of Tisagenlecleucel in Children and Young Adults With B-Cell Acute Lymphoblastic Leukemia(B-ALL)

NCT03666000Phase 1Recruiting

Dose-escalation and Dose-expansion Study of Safety of Azer-cel (PBCAR0191) in Participants With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)

Scroll to load more

Research Network

Activity Timeline