Observation on the Frailty Status of Lung Cancer Patients

NCT06448455 | Recruiting

• 1 other identifier: LM2024248
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

Using the Integrated Conceptual Model of Frailty (ICMF) and Frailty Framework among Vulnerable Population (FFVP) as theoretical basis, the frailty status of lung cancer patients is described, and the physiological, psychological, and social frailty of lung cancer patients are comprehensively evaluated and analyzed. The influencing factors related to frailty are explored, in order to provide a basis for effective intervention research on lung cancer patients in the future.

Conditions

Lung Cancer

Keywords

Lung cancer; Frailty; Factor

Outcome Measures

Primary Outcomes (1)

• Frailty

  Filburg Frailty Indicator，The score range is 0-55 points, and patients with ≥ 2points are diagnosed as debilitated. The higher the score of the total scale, the more serious the weakness.

  First day of admission

Secondary Outcomes (3)

• Sleep Quality

  First day of admission

• Anxiety

  First day of admission

• Depression

  First day of admission

Study Arms (1)

Lung cancer patients

Through convenience sampling, lung cancer patients who were hospitalized and outpatients in the cancer chemotherapy Department of Peking University Third Hospital were selected as the research objects of this study.

Other: Observation

Interventions

Observation OTHER

Collect relevant data of patients

Lung cancer patients

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

This study will select lung cancer patients who are hospitalized and outpatients in the cancer chemotherapy Department of Peking University Third Hospital as the research object through convenient sampling.

You may qualify if:

• Lung cancer was diagnosed by pathology or cytology;
• Age ≥ 18 years;
• Be able to complete this questionnaire independently or under the guidance of the researcher;
• Informed consent and voluntary participation in this study.

You may not qualify if:

• Serious physical diseases (heart, lung, kidney and other important organ failure);
• Patients with a history of dementia, mental illness, intellectual disability, and cognitive impairment;
• Blind, deaf and aphasic patients;
• Participate in other studies.

Sponsors & Collaborators

• Peking University Third Hospital: lead

Study Sites (1)

Peking University Third Hospital

Beijing, Beijing Municipality, 100083, China

RECRUITING

Related Publications (5)

• Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021 May;71(3):209-249. doi: 10.3322/caac.21660. Epub 2021 Feb 4.

  PMID: 33538338 BACKGROUND

• Shi JF, Wang L, Wu N, Li JL, Hui ZG, Liu SM, Yang BY, Gao SG, Ren JS, Huang HY, Zhu J, Liu CC, Fan JH, Zhao SJ, Xing PY, Zhang Y, Li N, Lei WD, Wang DB, Huang YC, Liao XZ, Xing XJ, Du LB, Yang L, Liu YQ, Zhang YZ, Zhang K, Qiao YL, He J, Dai M; LuCCRES Group. Clinical characteristics and medical service utilization of lung cancer in China, 2005-2014: Overall design and results from a multicenter retrospective epidemiologic survey. Lung Cancer. 2019 Feb;128:91-100. doi: 10.1016/j.lungcan.2018.11.031. Epub 2018 Nov 24.

  PMID: 30642458 BACKGROUND

• Ruiz J, Miller AA, Tooze JA, Crane S, Petty WJ, Gajra A, Klepin HD. Frailty assessment predicts toxicity during first cycle chemotherapy for advanced lung cancer regardless of chronologic age. J Geriatr Oncol. 2019 Jan;10(1):48-54. doi: 10.1016/j.jgo.2018.06.007. Epub 2018 Jul 10.

  PMID: 30005982 RESULT

• Komici K, Bencivenga L, Navani N, D'Agnano V, Guerra G, Bianco A, Rengo G, Perrotta F. Frailty in Patients With Lung Cancer: A Systematic Review and Meta-Analysis. Chest. 2022 Aug;162(2):485-497. doi: 10.1016/j.chest.2022.02.027. Epub 2022 Feb 22.

  PMID: 35217002 RESULT

• Duan L, Cui H, Zhang W, Wu S. Symptoms and experiences of frailty in lung cancer patients with chemotherapy: A mixed-method approach. Front Oncol. 2022 Oct 6;12:1019006. doi: 10.3389/fonc.2022.1019006. eCollection 2022.

  PMID: 36276107 RESULT

MeSH Terms

Conditions

Lung Neoplasms; Frailty

Interventions

Observation

Condition Hierarchy (Ancestors)

Respiratory Tract Neoplasms; Thoracic Neoplasms; Neoplasms by Site; Neoplasms; Lung Diseases; Respiratory Tract Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Methods; Investigative Techniques

Study Officials

• Jing Wang

  Peking University Third Hospital Library

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Jing Wang

CONTACT

13699176380; nmwj0723@163.com

Xinhua Shi

CONTACT

13699176380; shixinhua325@163.com

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Head nurse

Study Record Dates

• First Submitted: June 3, 2024
• First Posted: June 7, 2024
• Study Start: April 1, 2024
• Primary Completion: July 1, 2024
• Study Completion: December 31, 2024
• Last Updated: June 10, 2024

Record last verified: 2024-06

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)