NCT06442956

Brief Summary

This study will examine the effect of heat stress on factors that influence musculoskeletal injury risk in firefighters. Participants will attend 4 data collection sessions. 1: informed consent, screening, and familiarization. 2: pre-tests (strength, balance, and movement quality). 3: heat stress (rapid or gradual) followed by post-tests (strength, balance, and movement quality). 4: heat stress (rapid or gradual) followed by post-tests.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
26

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2025

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 29, 2024

Completed
7 days until next milestone

First Posted

Study publicly available on registry

June 5, 2024

Completed
7 months until next milestone

Study Start

First participant enrolled

January 7, 2025

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 7, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 7, 2025

Completed
Last Updated

March 30, 2026

Status Verified

March 1, 2026

Enrollment Period

10 months

First QC Date

May 29, 2024

Last Update Submit

March 25, 2026

Conditions

Keywords

firefightermusculoskeletalsliptripfall

Outcome Measures

Primary Outcomes (5)

  • Forward-Step-Down Test

    a step-down task that is performed off a 20 cm box. Five repetitions are performed to give one score (minimum score 0, maximum score 6). A higher score is worse.

    Familiarization trials (session 1, recruitment); pre-testing (baseline, session 2 (approximately day 7)); post-control and post-experimental sessions (session 3 (approximately day 14) & 4 (approximately day 21)).

  • Y-Balance Test

    A dynamic balance test that is performed on the dominant leg, reaching in the anterior, posteromedial, and posterolateral directions. The length of reach is standardized to participants' leg length. A higher score is better, with 0 being the minimum distance and the maximum distance in anterior reach being 126cm, and the maximum posteromedial and posterolateral directions being 149cm.

    Familiarization trials (session 1, recruitment); pre-testing (baseline, session 2 (approximately day 7)); post-control and post-experimental sessions (session 3 (approximately day 14) & 4 (approximately day 21)).

  • Firefighter Specific Functional Balance Test

    A dynamic balance test performed by stepping down from a 15cm box, walking across a low beam (4cm high), and stepping up onto a 10cm box, turning around, and returning to the original box. 8 Trials are performed. In 4 trials, a bar is placed at 75% of the participant's height for them to negotiate while on the beam. A faster time with fewer errors is better.

    Familiarization trials (session 1, recruitment); pre-testing (baseline, session 2 (approximately day 7)); post-control and post-experimental sessions (session 3 (approximately day 14) & 4 (approximately day 21)).

  • Knee Flexor/Extensor Isokinetic Test

    Knee flexor/extensor isokinetic strength will be tested at 60°, 180°, and 300° per second from the seated position with 5, 10, and 10 concentric contractions for each speed. A higher reading of strength is better.

    Familiarization trials (session 1, recruitment); pre-testing (baseline, session 2 (approximately day 7)); post-control and post-experimental sessions (session 3 (approximately day 14) & 4 (approximately day 21)).

  • Hip Abductor/Adductor Isokinetic Test

    Hip abductor/adductor strength will be tested at 30°, 60°, and 120° per second from the standing position. A higher reading of strength is better.

    Familiarization trials (session 1, recruitment); pre-testing (baseline, session 2 (approximately day 7)); post-control and post-experimental sessions (session 3 (approximately day 14) & 4 (approximately day 21)).

Secondary Outcomes (1)

  • Injury Occurrence

    6 months, 12 months, 18 months, 24 months after session 4.

Study Arms (2)

Rapid Heat Stress

EXPERIMENTAL

Participants in the rapid heat stress arm will perform an exercise protocol on a treadmill in a hot, humid environment while wearing firefighter protective gear. This results in an uncompensable heat environment with a rapid increase in core temperature.

Other: Rapid Heat Condition

Gradual Heat Stress

ACTIVE COMPARATOR

Participants in the rapid heat stress arm will perform an exercise protocol on a treadmill in a hot, humid environment while wearing light exercise clothing. This results in an uncompensable heat environment but with a gradual increase in core temperature.

Other: Gradual Heat Condition

Interventions

The heat condition is the intervention. Personal protective equipment will be used to create the rapid heat stress condition, resulting in a rapid rise in core temperature. This will be in combination with the physiological heat produced by the treadmill protocol.

Rapid Heat Stress

The gradual heat condition is the control. Physiological heat will be produced by exercise on a treadmill, and light exercise clothing will help moderate the rise in core temperature.

Gradual Heat Stress

Eligibility Criteria

Age18 Years - 57 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • professional firefighter
  • healthy per the Physical Activity Readiness Questionnaire+ screening

You may not qualify if:

  • unable to swallow core temperature capsule
  • unable to follow pre-testing hydration criteria
  • musculoskeletal injury in the past 3 months that limits ability to perform outcome measures
  • females with known pregnancy (risk of hyperthermia to fetus)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

LSUHSC-Shreveport

Shreveport, Louisiana, 71103, United States

Location

Related Publications (27)

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    PMID: 31204598BACKGROUND
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    PMID: 9459534BACKGROUND
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    PMID: 10416998BACKGROUND
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    PMID: 10840867BACKGROUND
  • Coehoorn CJ, Neary JP, Krigolson OE, Service TW, Stuart-Hill LA. Firefighter salivary cortisol responses following rapid heat stress. J Therm Biol. 2022 Aug;108:103305. doi: 10.1016/j.jtherbio.2022.103305. Epub 2022 Aug 7.

    PMID: 36031202BACKGROUND
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    PMID: 36343724BACKGROUND
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    PMID: 31280804BACKGROUND
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    PMID: 11394259BACKGROUND
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    PMID: 5614624BACKGROUND
  • Games KE, Winkelmann ZK, McGinnis KD, McAdam JS, Pascoe DD, Sefton JM. Functional Performance of Firefighters After Exposure to Environmental Conditions and Exercise. J Athl Train. 2020 Jan;55(1):71-79. doi: 10.4085/1062-6050-75-18. Epub 2019 Dec 26.

    PMID: 31876454BACKGROUND
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    PMID: 21655382BACKGROUND
  • Lopes TJA, Simic M, Myer GD, Ford KR, Hewett TE, Pappas E. The Effects of Injury Prevention Programs on the Biomechanics of Landing Tasks: A Systematic Review With Meta-analysis. Am J Sports Med. 2018 May;46(6):1492-1499. doi: 10.1177/0363546517716930. Epub 2017 Jul 31.

    PMID: 28759729BACKGROUND
  • Nascimento LR, Teixeira-Salmela LF, Souza RB, Resende RA. Hip and Knee Strengthening Is More Effective Than Knee Strengthening Alone for Reducing Pain and Improving Activity in Individuals With Patellofemoral Pain: A Systematic Review With Meta-analysis. J Orthop Sports Phys Ther. 2018 Jan;48(1):19-31. doi: 10.2519/jospt.2018.7365. Epub 2017 Oct 15.

    PMID: 29034800BACKGROUND
  • McCallister E, Flower D. Can the forward-step-down test be used reliably in the clinical setting to assess movement changes resulting from maximal exertion? A pilot study. Internet Journal of Allied Health Sciences and Practice. 2020; 18(4).

    BACKGROUND
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    PMID: 11509498BACKGROUND
  • Orr R, Simas V, Canetti E, Schram B. A Profile of Injuries Sustained by Firefighters: A Critical Review. Int J Environ Res Public Health. 2019 Oct 16;16(20):3931. doi: 10.3390/ijerph16203931.

    PMID: 31623104BACKGROUND
  • Park KM, Cynn HS, Choung SD. Musculoskeletal predictors of movement quality for the forward step-down test in asymptomatic women. J Orthop Sports Phys Ther. 2013;43(7):504-10. doi: 10.2519/jospt.2013.4073. Epub 2013 Jun 11.

    PMID: 23756380BACKGROUND
  • Periard JD, Eijsvogels TMH, Daanen HAM. Exercise under heat stress: thermoregulation, hydration, performance implications, and mitigation strategies. Physiol Rev. 2021 Oct 1;101(4):1873-1979. doi: 10.1152/physrev.00038.2020. Epub 2021 Apr 8.

    PMID: 33829868BACKGROUND
  • Powers CM. The influence of abnormal hip mechanics on knee injury: a biomechanical perspective. J Orthop Sports Phys Ther. 2010 Feb;40(2):42-51. doi: 10.2519/jospt.2010.3337.

    PMID: 20118526BACKGROUND
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    PMID: 29287067BACKGROUND
  • Wohlgemuth K, Sekiguchi Y, Mota J. Overexertion and heat stress in the fire service: a new conceptual framework. Am J Ind Med. 2023 Aug;66(8):705-709. doi: 10.1002/ajim.23482. Epub 2023 Apr 16.

    PMID: 37062940BACKGROUND
  • Coehoorn, C. J., Stuart-Hill, L. A., Abimbola, W., Neary, J. P., & Krigolson, O. E. Firefighter neural function and decision-making following rapid heat stress. Fire Safety Journal, 2020; 118. https://doi.org/10.1016/j.firesaf.2020.103240

    BACKGROUND
  • Games, K. E., Winkelmann, Z. K., & Eberman, L. E. Physical Exertion Diminishes Static and Dynamic Balance in Firefighters. International Journal of Athletic Therapy and Training. 2020; 25(6), 318-322. https://doi.org/10.1123/ijatt.2019-0063

    BACKGROUND
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    PMID: 22715125BACKGROUND

MeSH Terms

Conditions

Occupational InjuriesHeat Stress DisordersLeg InjuriesBack Injuries

Condition Hierarchy (Ancestors)

Wounds and Injuries

Study Officials

  • Erin McCallister, DPT

    LSUHSC-Shreveport

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
CROSSOVER
Model Details: randomized crossover
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 29, 2024

First Posted

June 5, 2024

Study Start

January 7, 2025

Primary Completion

November 7, 2025

Study Completion

November 7, 2025

Last Updated

March 30, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will not share

Locations