Neutrophil Extracellular Traps (NETs) Mediated Killing of Carbapenem-resistant Pseudomonas Aeruginosa.
1 other identifier
observational
50
0 countries
N/A
Brief Summary
Aim of the work: To determine the killing ability of neutrophils to ATCC 27853, carbapenem-resistant P. aeruginosa. To compare between the ability of ATCC 27853, carbapenem-resistant P. aeruginosa to induce NETs formation. To quantify NETS formation in response to PMA, ATCC 27853, carbapenem-resistant P. aeruginosa using immunofluorescence. To determine the killing ability of NETs on ATCC 27853, carbapenem-resistant P. aeruginosa.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Jun 2024
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
May 29, 2024
CompletedStudy Start
First participant enrolled
June 1, 2024
CompletedFirst Posted
Study publicly available on registry
June 4, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
July 1, 2025
CompletedJune 4, 2024
June 1, 2024
1 year
May 29, 2024
June 3, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
Quantitification of neutrophils extracellular traps by immunofluroscrnce
Quantitification of neutrophils extracellular traps by indirect immunofluroscrnce
Three months
Interventions
No intervention on patient
Eligibility Criteria
Clinical isolates from different clinical samples including urine, blood, sputum, wound
You may qualify if:
- isolates will be isolated from different clinical samples including wound respiratory tract urine and blood. \_carbapenem-resistant P. aeruginosa isolates.
You may not qualify if:
- \_carbapenem-sensitive P. aeruginosa isolates.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- OTHER
- Time Perspective
- OTHER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant Lecturer at medical Microbilogy and Immunology department
Study Record Dates
First Submitted
May 29, 2024
First Posted
June 4, 2024
Study Start
June 1, 2024
Primary Completion
June 1, 2025
Study Completion
July 1, 2025
Last Updated
June 4, 2024
Record last verified: 2024-06