Passive Thoughts in Functional Movement Disorders

NCT06439017 | Not Yet Recruiting

• 1 other identifier: 125294
• Study Type: observational
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

Passive thoughts also known as mind-wandering are the thoughts that are not produced from the current task. When we aren't focused on a task that needs our full attention, our minds tend to drift from one thought to another. It is believed that mind wandering is the baseline or natural state of the mind, and we shift our focus only when needed for a task. Many areas of the brain are active during mind-wandering, and these areas together are called the brain's default network. An important part of this network is the right temporoparietal junction. Functional movement disorder (FMD) is characterized by unusual movements or walking difficulties that are not caused by a specific brain or nerve injury. Functional movement disorders are believed to be caused due to loss of sense of agency. The sense of agency is the awareness that one is responsible for their own actions. The brain network involved in the sense of agency is mainly located in the right side of the brain, especially in the right temporoparietal junction. In FMD patients, there is decreased connectivity between the right temporoparietal junction and other brain areas that control movement. Since both passive thoughts (mind wandering) and the sense of agency involve the temporoparietal junction, and because the sense of agency is abnormal in functional movement disorders (FMD), we plan to study passive thoughts in individuals with FMD. The study aims to find out how passive thoughts differ between individuals with FMD and healthy individuals. Passive thoughts will be measured using Mind Excessively Wandering Scale (MEWS).

Conditions

Functional Movement Disorder

Outcome Measures

Primary Outcomes (1)

• Passive thoughts questionnaire

  The Passive Thoughts Questionnaire assesses the severity of passive thoughts and their impact on daily life.

  Day 1

Study Arms (2)

Cases with functional movement disorders

The cases will complete the Mind Excessively Wandering Scale (MEWS) and World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0), a 36-item self-administered questionnaire. The individual responses will remain anonymous.

Other: Questionaire

Healthy controls

The controls will complete the Mind Excessively Wandering Scale (MEWS). The individual responses will remain anonymous.

Other: Questionaire

Interventions

Questionaire OTHER

The study will involve completing the Mind Excessively Wandering Scale (MEWS) and World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0), a 36-item self-administered questionnaire.

Cases with functional movement disorders; Healthy controls

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients diagnosed with a functional movement disorder will be included in the study.

You may qualify if:

• Diagnosed with a functional movement disorder by the neurologist.
• Able to understand and read English.

You may not qualify if:

• Unable to understand and read English.
• Diagnosed with dementia.

Sponsors & Collaborators

• Western University, Canada: lead

Study Sites (1)

Aditya Murgai

London, Ontario, N6A5A5, Canada

Location

MeSH Terms

Conditions

Conversion Disorder

Condition Hierarchy (Ancestors)

Somatoform Disorders; Mental Disorders

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Passive thoughts in functional movement disorders

Study Record Dates

• First Submitted: May 27, 2024
• First Posted: June 3, 2024
• Study Start: March 1, 2025
• Primary Completion (Estimated): December 1, 2027
• Study Completion (Estimated): December 1, 2027
• Last Updated: January 24, 2025

Record last verified: 2024-09

Data Sharing

• IPD Sharing: Will not share

Locations

CA (1)