Efficacy of Eye Movement Desensitization & Reprocessing vs Cognitive Behavioral Therapy in Post-Traumatic Stress and Comorbid Disorders in Pakistan

NCT06435052 | Recruiting

• 1 other identifier: 111
• Study Type: interventional
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

This Randomized Controlled Trial will check the efficacy of Eye Movement Desensitization \& Reprocessing vs Cognitive Behavioral Therapy in Post-Traumatic Stress and Comorbid Disorders in Pakistan

Conditions

Post Traumatic Stress Disorder; Depression, Anxiety

Keywords

Post Traumatic Stress Disorder; EMDR; CBT; Pakistan

Outcome Measures

Primary Outcomes (1)

• Post-traumatic stress disorder

  Post-traumatic stress disorder (PTSD) will be assessed using the Clinician-Administered PTSD Scale for DSM-5 (CAPS-5). The CAPS-5 scores will be utilized to determine the severity of PTSD symptoms. Typically, a CAPS-5 score of 40 or above will serve as the cutoff point for diagnosing PTSD.

  2 years

Secondary Outcomes (1)

• Depressive and Anxiety Symptoms

  2 years

Study Arms (2)

Eye Movement Desensitization & Reprocessing Therapy

EXPERIMENTAL

Eye Movement Desensitization and Reprocessing (EMDR) therapy will be administered face-to-face by a psychotherapist in a total of 12 sessions, with one session per week. The efficacy of EMDR therapy will be compared with Cognitive Behavioral Therapy (CBT) in the treatment of Post-Traumatic Stress Disorder (PTSD) in Pakistan.

Behavioral: Eye Movement Desensitization & Reprocessing Therapy

Cognitive Behavioral Therapy

ACTIVE COMPARATOR

Cognitive Behavioral Therapy (CBT) will be delivered face-to-face by a psychotherapist in a total of 14 sessions, with one session per week. The efficacy of CBT will be compared with Eye Movement Desensitization and Reprocessing therapy in the treatment of Post-Traumatic Stress Disorder in Pakistan.

Behavioral: Cognitive Behavioral Therapy

Interventions

Eye Movement Desensitization & Reprocessing Therapy BEHAVIORAL

Eye Movement Desensitization and Reprocessing (EMDR) therapy will be administered face-to-face by a psychotherapist in a total of 12 sessions, with one session per week. The efficacy of EMDR therapy will be compared with Cognitive Behavioral Therapy in the treatment of Post-Traumatic Stress Disorder in Pakistan.

Eye Movement Desensitization & Reprocessing Therapy

Cognitive Behavioral Therapy BEHAVIORAL

Cognitive Behavioral Therapy will be comparatively checked with Eye Movement Desensitization \& Reprocessing Therapy for its efficacy. It will be administered by psychotherapist in 14 sessions (each session per week)

Cognitive Behavioral Therapy

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may not qualify if:

• The following patients will be excluded:
• Patients below the age of 15 years and above 60 years, since this study is neither on children nor on old aged patients;
• Patients who can't move their hands and eyes/or can't perform basic movements;
• Patients who are unconscious for longer periods and unable to recover consciousness;
• Patients not meeting the basic screening criteria of PTSD/ PTSD is not the main problem;
• Patients with severe intellectual impairments, since such patients are difficult to communicate

Sponsors & Collaborators

• Khushal Khan Khattak Univeristy, Karak, Pakistan: lead

Study Sites (1)

Anwar Khan

Karak, 27200, Pakistan

RECRUITING

MeSH Terms

Conditions

Stress Disorders, Post-Traumatic; Depression; Anxiety Disorders

Interventions

Cognitive Behavioral Therapy

Condition Hierarchy (Ancestors)

Stress Disorders, Traumatic; Trauma and Stressor Related Disorders; Mental Disorders; Behavioral Symptoms; Behavior

Intervention Hierarchy (Ancestors)

Behavior Therapy; Psychotherapy; Behavioral Disciplines and Activities

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: OTHER
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr. Anwar Khan, Assistant Professor of Organizational Psychology

Study Record Dates

• First Submitted: February 1, 2023
• First Posted: May 30, 2024
• Study Start: August 15, 2022
• Primary Completion: August 15, 2024
• Study Completion: August 15, 2025
• Last Updated: May 30, 2024

Record last verified: 2024-05

Locations

PA (1)