NCT06419400

Brief Summary

A 6-month randomised controlled trial to evaluate the impact of text message support on symptom control and inhaler adherence for patients with asthma and/or COPD

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
6,053

participants targeted

Target at P75+ for not_applicable asthma

Timeline
Completed

Started Apr 2022

Geographic Reach
1 country

7 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2022

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 15, 2023

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2023

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

May 14, 2024

Completed
3 days until next milestone

First Posted

Study publicly available on registry

May 17, 2024

Completed
Last Updated

May 20, 2024

Status Verified

May 1, 2024

Enrollment Period

1.5 years

First QC Date

May 14, 2024

Last Update Submit

May 17, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Improved self-reported medication taking as measured by the The Medication Adherence Report Scale (MARS-5) Questionnaire

    Changes in the MARS-5 Questionnaire

    Baseline to 13 and 26 weeks

Secondary Outcomes (4)

  • Improved control of asthma symptoms as measured by the Asthma Control Test

    Baseline to 13 and 26 weeks (for asthma patients)

  • A reduction in the interval between patients requesting preventer inhaler prescriptions

    Baseline to 13 and 26 weeks

  • Difference in emergency admissions

    Over 26 weeks

  • Differences in NHS utilisation

    Over 26 weeks

Study Arms (2)

Supportive Text Messagses

EXPERIMENTAL

The intervention group will receive a series of supportive text messages over the 6 month trial period, varying in content and frequency. They will also be asked to provide self reported data on their symptoms and their adherence at 3 points in time (start, mid-point, and end of trial).

Behavioral: Supportive text messages

Control Group

NO INTERVENTION

The control group will receive no supportive text messages over the period of the trial. They will be asked to only provide self reported data on their symptoms and their adherence at 3 points in time (start, mid-point, and end of trial).

Interventions

The intervention group will receive a series of supportive text messages over the 6 month trial period, varying in content and frequency.

Supportive Text Messagses

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Willing and able to provide informed consent and to comply with the study instructions
  • Male and females age 18 or older
  • Confirmed diagnosis of asthma and/or COPD as recorded in the patient's GP medical record
  • Currently prescribed a preventer inhaler
  • Access to a mobile phone
  • Ability to check text messages on phone
  • Ability to read

You may not qualify if:

  • Inability to understand the study procedures
  • Inability or reluctance to provide responses to the study questionnaires
  • Inability to receive and respond to text messages

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (7)

University Medical Centre

Canterbury, Kent, CT2 7PB, United Kingdom

Location

Gravesend Medical Centre

Gravesend, Kent, DA12 2EN, United Kingdom

Location

Jubilee Medical Centre

Longfield, Kent, DA3 7QD, United Kingdom

Location

Marlowe Park Medical Centre

Rochester, Kent, ME2 2PW, United Kingdom

Location

High Oak Surgery

Dudley, West Midlands, United Kingdom

Location

Lion Health

Stourbridge, West Midlands, DY8 3SS, United Kingdom

Location

Wordsley Green Health Centre

Worsley, West Midlands, DY8 5PD, United Kingdom

Location

MeSH Terms

Conditions

AsthmaPulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Luke Twelves

    Lindus Health

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 14, 2024

First Posted

May 17, 2024

Study Start

April 1, 2022

Primary Completion

September 15, 2023

Study Completion

November 1, 2023

Last Updated

May 20, 2024

Record last verified: 2024-05

Data Sharing

IPD Sharing
Will not share

Locations