Hand Training Device For Cognitive Care

NCT06417034 | Completed

• 1 other identifier: A-ER-110-485
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

Previous studies indicated that auditory stimulation as an external cue might have positive impacts on sensorimotor synchronization. Additionally, according to previous reports apart from traditional interventions, digitized game-based device, such as FTOMBVG, are beneficial for the brain activation in elderly. Moreover, enhanced finger force control and coordination lead to better hand dexterity and is believed to eventually improve life independence in the healthy elderly and the elderly with cognitive decline. Therefore, this study aims to develop an advanced systems based on the previous one, that can provide hand function rehabilitation, cognitive training, and emotional comfort for the elderly or people suffer from cognitive deficiency. They can enhance their finger force control or visual to motor synchronization by music embedded during the gaming process.

Conditions

Healthy Elderly; Mild Cognitive Impairment (MCI)

Keywords

Functional near infrared spectroscopy; Parameters of digit force independence; Pressing Evaluation and Training System

Outcome Measures

Primary Outcomes (3)

• Oxygenated hemoglobin (HbO)

  The Oxygenated hemoglobin (HbO) was measured while the participants play the game under both conditions

  30 minutes

• Montreal Cognitive Assessment (MoCA) test

  The Montreal Cognitive Assessment (MoCA) was designed as a rapid screening instrument for mild cognitive dysfunction. It assesses different cognitive domains: Short term memory, Visuospatial abilities, Executive functions, Attention, concentration and working memory, Language, Orientation to time and place. The sensitivity of MoCA for detecting MCI is 90%.

  10 minutes

• EN value

  The force independence is collected from the data during force control game in each evaluation session. The parameter of force independence is an index of five digits overall enslaving presented as EN.

  5 minutes

Secondary Outcomes (1)

• Maximum voluntary isometric contraction (MVIC)

  10 seconds

Study Arms (2)

Music-based game training

EXPERIMENTAL

Subjects will be asked to press their finger while a series of archery target continuously drop down and pass by the bottom line follow the beats of music melody on Tipr.

Device: Game Software

Non music-based game training

ACTIVE COMPARATOR

The background music will be disabled. Subjects need to press equally amount of force in certain tolerance that been set by only the visual cue on Tipr.

Device: Game Software

Interventions

Game Software DEVICE

The software is interfaced with a modified version of Frets on Fire (FOF)-an open source computer game similar to Guitar Hero.

Music-based game training; Non music-based game training

Eligibility Criteria

• Age: 65 Years - 90 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)

You may qualify if:

• Ability to communicate in Mandarin Chinese or Taiwanese
• MCI, according to clinical neurological assessment, Montreal Cognitive Assessment (MoCA):≦25\&≧19
• Ability to perform ADL independently, no hand function disability
• Voluntarily participation and ability to sign the informed consent form

You may not qualify if:

• Alzheimers disease diagnosed by physicians or meeting the diagnostic criteria for dementia
• Physician's diagnosis of stroke
• Any mental illness or behavior problems and inability to cooperate with the trainer
• Visual impairment or hand diseases resulting in an inability to perform finger press
• received other cognitive or physical training in the past year
• any sight, hearing, or communication impairment

Sponsors & Collaborators

• National Cheng-Kung University Hospital: lead

Study Sites (1)

National Cheng Kung University

Tainan, 701, Taiwan

Location

Related Publications (62)

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MeSH Terms

Conditions

Cognitive Dysfunction

Condition Hierarchy (Ancestors)

Cognition Disorders; Neurocognitive Disorders; Mental Disorders

Study Officials

• Fong-Chin Su, PhD

  Chair Professor

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Chair Professor

Study Record Dates

• First Submitted: May 12, 2024
• First Posted: May 16, 2024
• Study Start: March 27, 2022
• Primary Completion: April 11, 2022
• Study Completion: April 11, 2022
• Last Updated: May 28, 2024

Record last verified: 2024-05

Locations

TW (1)