Serum Irisin Level In Leprosy Patients

NCT06416033 | Completed DMC

• 1 other identifier: Irisin Level In Leprosy
• Study Type: observational
• Target: 58
• Locations: 1 country
• Sites: 1

Brief Summary

• Measurement of plasma irisin level in leprosy patients.
• Correlation of plasma irisin level between leprosy patients and healthy controls.
• Correlation of plasma irisin level in different leprosy types.

Conditions

Leprosy

Keywords

Leprosy; Irisin; tuberculoid leprosy; lepromatous leprosy

Outcome Measures

Primary Outcomes (1)

• measurement of Serum Irisin

  comparing the plasma irisin levels in leprosy patients with healthy Participants

  24 hours

Study Arms (2)

Group A :(Leprosy Group)

About 29 patients newly affected with Leprosy and The plasma irisin level of the participants will be measured by enzyme-linked immunosorbent assay (ELISA).

Procedure: Serum Irisin

Group B:(Control Group)

About 29 apparently healthy individuals and The plasma irisin level of the participants will be measured by enzyme-linked immunosorbent assay (ELISA).

Procedure: Serum Irisin

Interventions

Serum Irisin PROCEDURE

Measurement of plasma irisin level in leprosy patients.

Group A :(Leprosy Group); Group B:(Control Group)

Eligibility Criteria

• Age: 15 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Study will include patients with leprosy and healthy controls attending in the outpatient clinic of Dermatology, Venereology and Andrology, Aswan University Hospital, Aswan University.

You may qualify if:

• \- New cases of leprosy patients.

You may not qualify if:

• Old cases with leprosy.
• Patients with cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM).
• Patients with polycystic ovary syndrome (PCOS), Nonalcoholic fatty liver disease (NAFLD) and metabolic bone diseases.

Sponsors & Collaborators

• Aswan University: lead

Study Sites (1)

Aswan University Hospital

Aswān, Egypt

Location

MeSH Terms

Conditions

Leprosy; Leprosy, Tuberculoid; Leprosy, Lepromatous

Condition Hierarchy (Ancestors)

Mycobacterium Infections, Nontuberculous; Mycobacterium Infections; Actinomycetales Infections; Gram-Positive Bacterial Infections; Bacterial Infections; Bacterial Infections and Mycoses; Infections; Leprosy, Paucibacillary; Leprosy, Multibacillary

Study Officials

• Moustafa El Taieb, Professor

  Department of Dermatology, Venereology and Andrology Faculty of Medicine, Aswan University

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Resident at Dermatology, Venereology and Andrology

Study Record Dates

• First Submitted: May 10, 2024
• First Posted: May 16, 2024
• Study Start: January 1, 2024
• Primary Completion: July 1, 2024
• Study Completion: July 15, 2024
• Last Updated: November 8, 2024

Record last verified: 2024-05

Locations

EG (1)