Tapse/Pasp General Anesthesia
Prediction of TAPSE/PASP Ratio for Hypotension Due to General Anesthesia Induction
1 other identifier
observational
52
1 country
1
Brief Summary
TAPSE, one of the methods for evaluating right ventricular systolic function; It is a bar parameter that can easily measure apex-basal shortening and provides specific information about global RV function. TAPSE/PASP can be calculated as load-independent parameters to evaluate RV function. Because RV function is sensitive to change in afterload, known as the RV-pulmonary circulation (PC) connection. This study aims to identify patients who are candidates for hypotensive events due to general anesthesia in a hemodynamically stable population.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started May 2024
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
May 10, 2024
CompletedStudy Start
First participant enrolled
May 15, 2024
CompletedFirst Posted
Study publicly available on registry
May 16, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 15, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
March 15, 2025
CompletedJuly 30, 2024
May 1, 2024
8 months
May 10, 2024
July 29, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
1. tension
Intraoperative systolic arterial tension, diastolic arterial tension and mean arterial tension will be taken and recorded for the patients.
4-5 hours]
Study Arms (2)
Hypotension
Patients with a 30% decrease in SBP from baseline and a decrease in MAP below 65 mmHg in the first 10 minutes after anesthesia induction will be considered to have hypotension.
none hypotension
Patients who do not have a 30% decrease from the baseline in SBP and a decrease in MAP below 65 mmHg in the first 10 minutes after anesthesia induction will be considered as not having hypotension.
Interventions
MAP below 55 mmHg or long-term (2 minutes or more) hypotensive attacks will be treated with ephedrine 0.1mg/kg.
Eligibility Criteria
ASA1-3 patients aged 18-75 who will undergo elective surgery
You may qualify if:
- Written informed consent;
- years old
- ASA Physical Status 1-3;
- Patients planned for surgery
You may not qualify if:
- The patient is pregnant
- After cardiac surgery
- Severe pulmonary hypertension
- Severe valve disease
- Hypertrophic or dilated cardiomyopathy
- Presence of acute myocardial infarction
- Patients with severe visual or hearing impairment/disability
- ASA physical status IV or V
- Ischemic heart disease, conduction disorder.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Ferdi Gülaştı
Aydin, 09020, Turkey (Türkiye)
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 1 Day
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- ASS. PROF. DR
Study Record Dates
First Submitted
May 10, 2024
First Posted
May 16, 2024
Study Start
May 15, 2024
Primary Completion
January 15, 2025
Study Completion
March 15, 2025
Last Updated
July 30, 2024
Record last verified: 2024-05