NCT06411327

Brief Summary

Cognitive aids are decision support tools that present prompts to encourage recall of information, thus freeing up mental resources to increase the likelihood of desired behaviors. Cognitive aids have been trialed in different forms for use during resuscitation, including pocket reference cards and digital apps. Simulation-based studies of cognitive aid used during cardiac arrest events have shown improved adherence to guidelines, improved time to completing critical tasks, and reduced rate of critical errors. Unfortunately, existing pocket reference cards and mobile apps have significant flaws - they all require providers to search through content to identify relevant information. In the proposed study, the investigators will evaluate the impact of an enhanced system, InterFACE-AR, which provides role-specific decision support to the team leader and medication nurse through AR devices, while concurrently optimizing team situational awareness by displaying a roadmap for patient care on the LCD screen. Clinical data will be collected from the mobile app on a tablet used by the charting nurse. The trial aims to assess the individual and combined effectiveness of InterFACE-AR components (i.e. AR devices and LCD screen) on adherence to AHA resuscitation guidelines during simulated cardiac arrest by conducting a randomized controlled trial with a factorial design.

Trial Health

65
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
400

participants targeted

Target at P75+ for not_applicable

Timeline
26mo left

Started Sep 2025

Typical duration for not_applicable

Status
not yet recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress24%
Sep 2025Jun 2028

First Submitted

Initial submission to the registry

May 8, 2024

Completed
5 days until next milestone

First Posted

Study publicly available on registry

May 13, 2024

Completed
1.3 years until next milestone

Study Start

First participant enrolled

September 1, 2025

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2027

Expected
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2028

Last Updated

March 28, 2025

Status Verified

March 1, 2025

Enrollment Period

2.3 years

First QC Date

May 8, 2024

Last Update Submit

March 25, 2025

Conditions

Keywords

Cardiopulmonary arrestCardiac arrestCognitive aidDecision supportSimulation

Outcome Measures

Primary Outcomes (1)

  • Time to epinephrine

    Time to epinephrine administration, in seconds

    During event

Secondary Outcomes (19)

  • Time to initiation of CPR

    During event

  • Time to defibrillation

    During event

  • Time to amiodarone administration

    During event

  • Time to intubation

    During event

  • Medication errors

    During event

  • +14 more secondary outcomes

Study Arms (4)

Control Arm

NO INTERVENTION

AHA Pocket Reference Card - all participants will have access to the AHA pocket reference card, which is the mostly commonly used cognitive aid during resuscitation.

Augmented Reality Only

EXPERIMENTAL

Augmented Reality Devices - data collected from the Guiding-Pad app will be fed to two AR devices (i.e. team leader and medication nurse), which will provide role-specific decision support for these two providers.

Device: Augmented reality

LCD Screen Only

EXPERIMENTAL

LCD Screen - data collected from the Guiding-Pad app will be fed to the LCD screen, which will be mounted on a wall, in clear view for the entire resuscitation team to see.

Device: LCD Screen

Augmented Reality + LCD Screen (Full InterFACE-AR System)

EXPERIMENTAL

InterFACE-AR System - data collected from the Guiding-Pad app will be fed to the two AR devices (i.e. team leader and medication nurse) to provide role-specific decision support, and to the LCD screen, in clear view for the entire resuscitation team to see.

Device: Augmented realityDevice: LCD Screen

Interventions

Augmented Reality Devices - data collected from the Guiding-Pad app will be fed to two AR devices (i.e. team leader and medication nurse), which will provide role-specific decision support for these two providers.

Also known as: AR
Augmented Reality + LCD Screen (Full InterFACE-AR System)Augmented Reality Only

LCD Screen - data collected from the Guiding-Pad app will be fed to the LCD screen, which will be mounted on a wall, in clear view for the entire resuscitation team to see.

Also known as: LCD
Augmented Reality + LCD Screen (Full InterFACE-AR System)LCD Screen Only

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • \- attending physician, fellow, or senior resident in pediatric emergency medicine, adult emergency medicine, pediatric intensive care, pediatric anesthesia or general pediatrics.
  • \- nurse in pediatric emergency medicine, pediatric intensive care, pediatric anesthesia, pediatric surgery or general pediatrics.
  • \- pediatric attending physician, resident, fellow, nurse or respiratory therapist. All participants must have prior basic life support training.

You may not qualify if:

  • Decline to provide informed consent
  • previously enrolled
  • unable to perform tasks required of the role.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Heart Arrest

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular Diseases

Study Officials

  • Adam Cheng, MD

    University of Calgary

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Masking Details
Masking not possible given the nature of the intervention(s)
Purpose
TREATMENT
Intervention Model
FACTORIAL
Model Details: Our factorial study design will assess the individual and synergistic impact of two interventions designed to provide decision support: (a) Augmented reality devices; and (b) LCD Screen. Intervention A: Augmented Reality Devices Intervention B: LCD Screen Intervention C: InterFACE-AR System Control Group: AHA Pocket Reference Card
Sponsor Type
NETWORK
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Director, Research and Development

Study Record Dates

First Submitted

May 8, 2024

First Posted

May 13, 2024

Study Start

September 1, 2025

Primary Completion (Estimated)

December 31, 2027

Study Completion (Estimated)

June 30, 2028

Last Updated

March 28, 2025

Record last verified: 2025-03

Data Sharing

IPD Sharing
Will not share