Fetal Brain Ultrasound

NCT06410391 | Completed

• 1 other identifier: FBUS
• Study Type: observational
• Target: 110
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of our study is to determine the range of frontal horn sizes (both upside and downside) in healthy fetuses over gestation and to determine how far FHs are from the midline . Also to determine the range of cavum septi pellucidi and Corpus callosum sizes . Also, to determine whether the maternal body mass index (BMI) affects rates of visualized and non-visualized CSP and CC.

Conditions

Fetal Anomaly

Outcome Measures

Primary Outcomes (1)

• Determine the range of lateral ventricles diameter in healthy fetuses at different gestational ages.,

  Diameter of Lateral ventricles measured by ultrasound in millimeters

  5 months

Secondary Outcomes (1)

• measurement of Cavum septum and Corpus callosum

  5 months

Interventions

Ultrasound RADIATION

Gestational age, biparietal diameter and head circumference are measured. then 2 techniques are used according to the 2007 International Society of Ultrasound in Obstetrics and Gynecology guidelines for a US evaluation of the fetal central nervous system (CNS) (10) : 1- the axial transventricular technique including the posterior portions of the lateral ventricles, falx, CSP, and Frontal horn 2- the trans-cerebellar technique, including the cerebellum, cisternal magna, cerebellar peduncles, CSP, and FHs. CSP visualization and width, FH width, anterior horn width (AHW), center from the horn distance (CFHD), upside and downside measurement. The corpus callosum is identified in the midsagittal plane. The image selected for CC measurement in addition to cerebellar vermis and cisterna magna

Eligibility Criteria

• Age: 15 Years - 45 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

All healthy pregnant women came to fetal medicine unit at 15 to 36 weeks

You may qualify if:

• pregnant woman 15 weeks to 36 weeks

You may not qualify if:

• congenital malformations
• Multiple pregnancy
• intrauterine infection
• fetuses with Fetal growth restriction

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Women Health Hospital

Asyut, Egypt

Location

MeSH Terms

Conditions

Congenital Abnormalities

Interventions

High-Energy Shock Waves

Condition Hierarchy (Ancestors)

Congenital, Hereditary, and Neonatal Diseases and Abnormalities

Intervention Hierarchy (Ancestors)

Ultrasonic Waves; Sound; Radiation, Nonionizing; Radiation; Physical Phenomena

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Lecturer of Obs& Gyn. Specialist of Urogynecology

Study Record Dates

• First Submitted: May 3, 2024
• First Posted: May 13, 2024
• Study Start: June 15, 2024
• Primary Completion: December 2, 2024
• Study Completion: December 11, 2024
• Last Updated: December 18, 2024

Record last verified: 2024-06

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)