The Cervical Length and Thickness of Cesarean Section Scar With Preterm Labor

NCT04554745 | Completed

• 1 other identifier: Preterm labor and previous cs
• Study Type: interventional
• Target: 260
• Locations: 1 country
• Sites: 1

Brief Summary

Although the Cesarean section is one of the most common obstetric operations around the world, the World Health Organization recognizes that where cesarean rates are higher than 10%, there is no increase in beneficial maternal and newborn outcomes. some researchers noted that in countries where cesarean rates are above 15%, populations experience higher maternal, infant, and neonatal mortality rates. infants born by cesarean delivery are more likely to require neonatal intensive care unit and have greater respiratory complications, and higher odds for childhood asthma, and obesity. Preterm is defined as babies born alive before completing 37 weeks of pregnancy. Preventing Preterm birth is a global priority due to increased risk for neonatal morbidity and mortality.

Conditions

Preterm Labor

Outcome Measures

Primary Outcomes (1)

• Number of preterm labor in both groups

  6 months

Secondary Outcomes (2)

• number of babies will enter the neonatal intensive care unit

  6 months

• Gestational age at time of delivery

  6 months

Study Arms (2)

Non-scared uterus of pregnant women

OTHER

Radiation: Ultrasound

Scared uterus of pregnant women

OTHER

Radiation: Ultrasound

Interventions

Ultrasound RADIATION

ultrasound assessment of pregnant women

Non-scared uterus of pregnant women; Scared uterus of pregnant women

Eligibility Criteria

• Age: 20 Years - 35 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• singleton pregnant
• gestational age at 18 weeks
• previous vaginal or Cesarean section

You may not qualify if:

• twins pregnancy in their second birth
• previous preterm labor
• diabetic during the second pregnancy
• hypertensive during the second pregnancy
• cigarette use during the second pregnancy
• congenital anomalies

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Amr

Asyut, 71111, Egypt

Location

Related Publications (8)

• Hu HT, Xu JJ, Lin J, Li C, Wu YT, Sheng JZ, Liu XM, Huang HF. Association between first caesarean delivery and adverse outcomes in subsequent pregnancy: a retrospective cohort study. BMC Pregnancy Childbirth. 2018 Jun 28;18(1):273. doi: 10.1186/s12884-018-1895-x.

  PMID: 29954355 BACKGROUND

• Urquia ML. Is the association between previous caesarean section and preterm delivery causal? BJOG. 2020 Apr;127(5):618. doi: 10.1111/1471-0528.16099. Epub 2020 Feb 10. No abstract available.

  PMID: 31953981 BACKGROUND

• Visser L, Slaager C, Kazemier BM, Rietveld AL, Oudijk MA, de Groot C, Mol BW, de Boer MA. Risk of preterm birth after prior term cesarean. BJOG. 2020 Apr;127(5):610-617. doi: 10.1111/1471-0528.16083. Epub 2020 Feb 24.

  PMID: 31883402 BACKGROUND

• Wang M, Kirby A, Gibbs E, Gidaszewski B, Khajehei M, Chua SC. Risk of preterm birth in the subsequent pregnancy following caesarean section at full cervical dilatation compared with mid-cavity instrumental delivery. Aust N Z J Obstet Gynaecol. 2020 Jun;60(3):382-388. doi: 10.1111/ajo.13058. Epub 2019 Sep 12.

  PMID: 31514230 BACKGROUND

• Williams CM, Asaolu I, Chavan NR, Williamson LH, Lewis AM, Beaven L, Ashford KB. Previous cesarean delivery associated with subsequent preterm birth in the United States. Eur J Obstet Gynecol Reprod Biol. 2018 Oct;229:88-93. doi: 10.1016/j.ejogrb.2018.08.013. Epub 2018 Aug 11.

  PMID: 30130688 BACKGROUND

• Yasseen Iii AS, Bassil K, Sprague A, Urquia M, Maguire JL. Late preterm birth and previous cesarean section: a population-based cohort study. J Matern Fetal Neonatal Med. 2019 Jul;32(14):2400-2407. doi: 10.1080/14767058.2018.1438397. Epub 2018 Feb 21.

  PMID: 29415589 BACKGROUND

• Zhang N, Chen H, Xu Z, Wang B, Sun H, Hu Y. Pregnancy, Delivery, and Neonatal Outcomes of In Vitro Fertilization-Embryo Transfer in Patient with Previous Cesarean Scar. Med Sci Monit. 2016 Sep 16;22:3288-95. doi: 10.12659/msm.900581.

  PMID: 27636504 BACKGROUND

• Zhang Y, Zhou J, Ma Y, Liu L, Xia Q, Fan D, Ai W. Mode of delivery and preterm birth in subsequent births: A systematic review and meta-analysis. PLoS One. 2019 Mar 14;14(3):e0213784. doi: 10.1371/journal.pone.0213784. eCollection 2019.

  PMID: 30870524 BACKGROUND

MeSH Terms

Conditions

Obstetric Labor, Premature

Interventions

High-Energy Shock Waves

Condition Hierarchy (Ancestors)

Obstetric Labor Complications; Pregnancy Complications; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases

Intervention Hierarchy (Ancestors)

Ultrasonic Waves; Sound; Radiation, Nonionizing; Radiation; Physical Phenomena

Study Officials

• Ahmed Abo Al Fadl Elsayed Mohammed, Asst.prof

  Assiut University

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant professor

Study Record Dates

• First Submitted: September 13, 2020
• First Posted: September 18, 2020
• Study Start: February 1, 2021
• Primary Completion: February 1, 2022
• Study Completion: August 1, 2022
• Last Updated: December 13, 2022

Record last verified: 2022-12

Locations

EG (1)