NCT06400134

Brief Summary

The aim of this study is to investigate the relationship between cognitive functions with physical performance, grip strength, walking speed, mobility, and frailty in geriatric individuals. Decline in cognitive function and decline in physical performance are generally associated with advanced age. Cognitive dysfunction is a natural consequence of ageing and is an important factor in maintaining quality of life and independence. Investigating the relationship between cognition, physical performance, mobility, and frailty has become a challenging issue in recent years. However, there is a need to further clarify the direction of this cognitive-motor link.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jun 2022

Shorter than P25 for all trials

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2022

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 15, 2022

Completed
15 days until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2022

Completed
1.6 years until next milestone

First Submitted

Initial submission to the registry

April 30, 2024

Completed
6 days until next milestone

First Posted

Study publicly available on registry

May 6, 2024

Completed
Last Updated

May 6, 2024

Status Verified

May 1, 2024

Enrollment Period

4 months

First QC Date

April 30, 2024

Last Update Submit

May 2, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Cognition function

    The Standardised Mini Mental Test, which evaluates cognitive functions, consists of a total of 30 points. Those who score 24 and below are evaluated for dementia.

    4 month

Secondary Outcomes (5)

  • Physical Performance

    4 month

  • Grip Strength

    4 month

  • Walking speed

    1 month

  • Mobility

    4 month

  • Frailty

    4 month

Study Arms (1)

Geriatric individuals

Volunteer healthy geriatric individuals aged 65 years and over

Other: Cognitive FunctionOther: Physical PerformanceOther: Grip StrengthOther: Walking speedOther: MobilityOther: Fraility

Interventions

The Standardized Mini Mental Test (SMMT) was used to evaluate the cognitive status of the geriatric individuals'. In the test, which has a total score of 30, those with a score of 24 or less are recommended to be evaluated for dementia.

Geriatric individuals

The Brief Physical Performance Battery (BPPB) was used to assess the physical performance of geriatric individuals. All three physical performance measures (balance, walking speed, getting up from the chair) were scored between 0-4 according to the duration of the activity, these scores were summed and the total score was determined between 0 (poor) and 12 (very good).

Geriatric individuals

Muscle strength was assessed with a hand grip dynamometer. In the geriatric individuals, less than 30 kg for men and less than 20 kg for women was considered as low hand grip strength.

Geriatric individuals

Walking speed was assessed with the 6-metre walk test. Speed was calculated by dividing each known distance by the time it took for each individual, on each trial, to walk from the start to the end points marked on the floor and then converting to m/s.

Geriatric individuals

The Time up Go test (TUG) was used for mobility. The risk of falling increases with increasing duration.

Geriatric individuals

Frailty assessment was performed using the FRAIL scale.The scale was scored by giving 0 or 1 point according to the answer given. The higher the score, the greater the fraility.

Geriatric individuals

Eligibility Criteria

Age65 Years - 82 Years
Sexall
Healthy VolunteersYes
Age GroupsOlder Adult (65+)
Sampling MethodProbability Sample
Study Population

Geriatric individuals

You may qualify if:

  • Volunteer healthy geriatric individuals aged 65 years and over
  • Able to walk independently

You may not qualify if:

  • Without neurological and rheumatological diseases,
  • Without acute musculoskeletal problems in the lower extremities

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Ankara Yıldırım Beyazıt University, Faculty of Health Sciences,Department of Physiotherapy and Rehabilitation

Ankara, Esenboğa, 06970, Turkey (Türkiye)

Location

Ankara Yıldırım Beyazıt University

Ankara, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Frailty

Interventions

Neuropsychological TestsPhysical Functional PerformanceHand StrengthWalking SpeedRange of Motion, Articular

Condition Hierarchy (Ancestors)

Pathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Psychological TestsBehavioral Disciplines and ActivitiesPhysical FitnessHealthPopulation CharacteristicsMuscle StrengthPhysical ExaminationDiagnostic Techniques and ProceduresDiagnosisMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological PhenomenaGaitWalkingLocomotionMovement

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
OTHER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 30, 2024

First Posted

May 6, 2024

Study Start

June 1, 2022

Primary Completion

September 15, 2022

Study Completion

September 30, 2022

Last Updated

May 6, 2024

Record last verified: 2024-05

Locations