NCT06393699

Brief Summary

patients with non carious cervical lesions suffer from dentin sensitivity and presence of cavitations and gingival recession. Restoring these lesions with different composites and evaluation of restorations every 6 months will be done to know the effect of different composite types and consistencies in retention of restorations of such lesions.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
52

participants targeted

Target at P25-P50 for not_applicable

Timeline
8mo left

Started May 2022

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress86%
May 2022Dec 2026

Study Start

First participant enrolled

May 14, 2022

Completed
1.3 years until next milestone

First Submitted

Initial submission to the registry

August 29, 2023

Completed
8 months until next milestone

First Posted

Study publicly available on registry

May 1, 2024

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 14, 2025

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 30, 2026

Expected
Last Updated

February 27, 2025

Status Verified

February 1, 2025

Enrollment Period

3.6 years

First QC Date

August 29, 2023

Last Update Submit

February 25, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Retention

    ability of resin composite restorations to be retained in the non carious cervical lesions

    18-24 months

Secondary Outcomes (1)

  • marginal staining

    18-24 months

Other Outcomes (2)

  • Marginal adaptation

    18-24 months

  • postoperative sensitivity

    18-24 months

Study Arms (4)

incremental

EXPERIMENTAL

application of increments of packable composite in non carious cervical lesions

Procedure: composite restoration

bulk fill heated

EXPERIMENTAL

application of heated composite as bulk in the lesions without incrementation after heating with caps warmer

Procedure: composite restoration

incremental heated

EXPERIMENTAL

application of composite in increments after being heated by caps warmer

Procedure: composite restoration

flowable

EXPERIMENTAL

application of flowable composite in non carious cervical lesions

Procedure: composite restoration

Interventions

different types of resin composite restorations will be used to restore NCCL

bulk fill heatedflowableincrementalincremental heated

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • \- Patients' age will range from 18 to 65 years.
  • Presence of at least 2 NCCLs in one side.
  • Patients with no medical condition could interfere with the routine dental care.
  • Patients who will be able to attend for each recall visit.
  • Patients with healthy periodontal tissues.
  • Cavities presenting no more than 50% of margins in enamel.

You may not qualify if:

  • Medically compromised patients.
  • Pregnant or breast-feeding patients.
  • Patients undergoing orthodontic treatment or bleaching treatment in the time of the study.
  • Patients with periodontal disease in the target area.
  • Patients presented with less than 20 teeth in the oral cavity.
  • Patients without antagonists.
  • Lesions superimposed with caries

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ain shams university

Cairo, Egypt

RECRUITING

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principle investigator

Study Record Dates

First Submitted

August 29, 2023

First Posted

May 1, 2024

Study Start

May 14, 2022

Primary Completion

December 14, 2025

Study Completion (Estimated)

December 30, 2026

Last Updated

February 27, 2025

Record last verified: 2025-02

Data Sharing

IPD Sharing
Will share
Shared Documents
STUDY PROTOCOL, SAP, ICF, CSR
Time Frame
expecting to have all data by october 2026

Locations