NCT06391047

Brief Summary

The objective of this study is to find out the effects of Mulligan's Squeeze technique added as a complementary treatment to the conventional physiotherapy for the management of meniscal derangement in knee osteoarthritis patients.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
26

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 2, 2024

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 22, 2024

Completed
3 days until next milestone

First Submitted

Initial submission to the registry

April 25, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 25, 2024

Completed
5 days until next milestone

First Posted

Study publicly available on registry

April 30, 2024

Completed
Last Updated

April 30, 2024

Status Verified

April 1, 2024

Enrollment Period

3 months

First QC Date

April 25, 2024

Last Update Submit

April 25, 2024

Conditions

Keywords

Knee Osteoarthritismanual therapy intervention; rehabilitationMenisci;

Outcome Measures

Primary Outcomes (2)

  • Numerical Pain Rating Scale (NPRS)

    It was used to record the level of knee pain

    Readings were taken at baseline, after 1st week and at end of 2nd week.

  • Goniometer

    It was used to find out the range of movement of knee flexion.

    Readings were taken at baseline, after 1st week and at end of 2nd week.

Secondary Outcomes (2)

  • Patient Specific Functional Scale (PSFS)

    Readings were taken at baseline, after 1st week and at end of 2nd week.

  • Knee injury and osteoarthritis outcome score (KOOS)

    Readings were taken at baseline, after 1st week and at end of 2nd week.

Study Arms (2)

Group A

EXPERIMENTAL

Group A was given hot pack at knee joint for 10-15min. Then the Mulligan's Squeeze Technique was applied. The patient in supine lying. The therapist placed thumb on joint line tenderness of knee. With the other thumb, the therapist reinforced the first thumb. The patient was asked to slowly flex knee. The therapist maintaining the thumb contact, applied the force centrally. The force was increased progressively as the knee moved towards full range of available flexion. At the end range, the therapist assisted the tibia to move towards more flexion with ulnar border of their hand. This position was maintained for a few seconds and the overpressure was applied. Then patient was asked to perform knee extension. As the knee moved towards extension the force applied from both thumbs was progressively reduced. At maximal extension, no force was applied. This was repeated 10 times in each set with total 3 sets. After this stretching and strengthening exercises were performed by patient.

Other: Mulligan's Squeeze Technique - manual therapyOther: Conventional Physiotherapy

Group B

ACTIVE COMPARATOR

Group B was given hot pack at knee joint for 10-15min. Then they were asked to perform stretching and strengthening exercises of the knee with at least 10 repetitions in each set and a total two sets in a day.

Other: Conventional Physiotherapy

Interventions

This technique was introduced by Brian R. Mulligan. In this technique the therapist places thumb along the tender joint margin and applies force centrally. The patient actively flexes knee and therapist progressively enhances force and at end applies overpressure. This force is decreased as knee moves towards extension. This method helps to maintain the meniscus in its normal position and corrects the derangement of meniscus.

Group A

It includes stretching and strengthening exercises of muscles of the knee joint.

Group AGroup B

Eligibility Criteria

Age30 Years - 55 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Pain during maximal knee flexion, pain when maximal extension of knee occurs
  • Both genders were taken; male and female
  • Age between 30 to 55 years
  • Tenderness along the line of joint
  • Complain or history of abnormal clicking sounds and/or popping of knee
  • If any of the mentioned special tests are positive: "Apley's compression and distraction test", the "Disco test or Thessaly's test" with almost 20° flexed position of knee, and "McMurray's test"
  • Participants who were willing to take part in the study

You may not qualify if:

  • Presence of any knee co-morbidities
  • Knee OA of Grade 4
  • ACL or some other knee ligament injury/tears
  • Contusion present on knee, fracture of knee
  • Knee dislocation
  • Knee instability due to any ligamentous injury
  • Constant pain or discomfort due to underlying reasons (e.g. hyper-algesia), and any other wound or ailment
  • Participant not willing to be a part of the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Allied Hospital

Faisalābad, Punjab Province, 38000, Pakistan

Location

MeSH Terms

Conditions

Osteoarthritis, KneeKnee Injuries

Condition Hierarchy (Ancestors)

OsteoarthritisArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic DiseasesLeg InjuriesWounds and Injuries

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Masking Details
The participants were randomly allocated to both groups and they did not know which one was experimental or control group.
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: It was a randomized controlled trial with two groups. One group was experimental while other group was active control group.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr Izza Ayub;PT Lecturer

Study Record Dates

First Submitted

April 25, 2024

First Posted

April 30, 2024

Study Start

February 2, 2024

Primary Completion

April 22, 2024

Study Completion

April 25, 2024

Last Updated

April 30, 2024

Record last verified: 2024-04

Locations