Is Low Flow Anaesthesia Feasible?

NCT06389669 | Completed

• 1 other identifier: Inonu LTI
• Study Type: observational
• Target: 785
• Locations: 1 country
• Sites: 1

Brief Summary

Although low-flow anaesthesia (LFA) has been described for many years and its benefits are known, its clinical use has been limited. Concerns about the risk of hypoxia contributed to this situation. Although the risk of hypoxia is almost prevented with advanced anaesthesia machines, the use of LFA has not reached the desired levels. However, in recent years, as adverse developments related to climate change have started to affect us all, LFA has started to be on the agenda of anaesthetists again. In this study, our aim is to examine the feasibility of its clinical use in order to popularise the use of LFA.

Conditions

Anesthesia

Keywords

Low Flow Anaesthesia; Closed-Circuit Anesthesia

Outcome Measures

Primary Outcomes (1)

• Feasibility of Low Flow Anaesthesia

  To determine the lowest amount of fresh gas flow, most suitable for the patient and, which can provide FiO2=40% level

  The measurement will start 10 minutes after the surgical incision and end 20 minutes later

Secondary Outcomes (1)

• Factors affecting oxygen consumption

  The measurement will start 10 minutes after the surgical incision and end 20 minutes later

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

ASA 1-2 patients who will undergo elective surgery under general anaesthesia in 38 operating rooms of Inonu University Faculty of Medicine will be prospectively recruited for 3 months (May-June-July). Emergency cases, patients under the age of 18 and over 65, laparoscopic surgeries, heart-lung surgeries that may impair oxygenation will not be included in the study.

You may qualify if:

• Patients undergoing surgery under general anaesthesia

You may not qualify if:

• Emergency operations
• Previously diagnosed heart, lung, liver and kidney disease
• Surgeries that may impair oxygenation (laparoscopic, Heart, Lung surgeries)

Sponsors & Collaborators

• Inonu University: lead

Study Sites (1)

Inonu Univercity

Malatya, 44280, Turkey (Türkiye)

Location

Study Officials

• Yusuf Z Colak, Assoc.Prof.

  Inonu University Anaesthesiology and Reanimation Department

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor, MD

Study Record Dates

• First Submitted: April 25, 2024
• First Posted: April 29, 2024
• Study Start: May 23, 2024
• Primary Completion: September 15, 2024
• Study Completion: September 20, 2024
• Last Updated: October 3, 2024

Record last verified: 2024-10

Locations

TU (1)