Shanghai Community Cohort Establishment and Follow-up

NCT04517513 | Unknown DMC

• 1 other identifier: Shanghai Community Cohort
• Study Type: observational
• Target: 80,000
• Locations: 1 country
• Sites: 1

Brief Summary

Our objective is to establish a natural population cohort in East China based on the latest scientific researches, preliminary findings of the project team, and a close cooperation model of the Specialist Medical Consortium. Firstly, we will focus on the information and management status of high-risk, single-patient, and co-occurring patient groups of cardio cerebral diseases such as coronary heart disease and stroke. We plan to integrate the questionnaire data and sample database information into the cardio-cerebral "co-prevention and management" information platform, in order to establish a cardiovascular and cerebrovascular disease management system. Secondly, we aim to develop a new risk prediction model for heart and brain diseases based on the big data platform, lead the establishment of the "co-prevention and management" innovation management model for cardio cerebral diseases, and explore an integrated and innovative health management model for the prevention and treatment of cardio cerebral diseases for China.

Conditions

Cardiovascular Diseases

Keywords

Cohort Study; Natural Population; China

Outcome Measures

Primary Outcomes (2)

• Cardiovascular and Cerebrovascular incidence

  Incidence of Cardiovascular and Cerebrovascular disease were calculated by age, gender and area compared by different health management mode.

  5 years

• Cardiovascular and Cerebrovascular mortality

  Mortality of Cardiovascular and Cerebrovascular disease were calculated by age, gender and area compared by different health management mode.

  5 years

Secondary Outcomes (1)

• Normalized management rate of Cardiovascular and Cerebrovascular disease

  5 years

Eligibility Criteria

• Age: 35 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Eligible residents from second-class medical units and community health service centers with mature conditions.

You may qualify if:

• Patients \>= 35y
• Registered Permanent residents or have lived for more than 5 years and have local social security medical insurance
• Patients with no serious physical disability and can communicate normally
• Patients who participate voluntarily and sign informed consent
• Patients whose diseases and deaths are managed by the local health department

You may not qualify if:

• Temporary residents and floating population
• Patients with serious health conditions and cannot participate in the investigation
• Patients who are unwilling to accept follow-up inspections of the project

Sponsors & Collaborators

• RenJi Hospital: lead
• Jinqiao Community Health Service Center of Pudong new area, Shanghai: collaborator
• Heqing Community Health Service Center of Pudong new area, Shanghai: collaborator
• Weifang Community Health Service Center of Pudong new area, Shanghai: collaborator
• Jinyang Community Health Service Center of Pudong new area, Shanghai: collaborator

Study Sites (1)

Ren Ji Hospital Afflited to School of Medicine, Shanghai Jiao Tong University

Shanghai, Shanghai Municipality, 200000, China

RECRUITING

Biospecimen

Retention: SAMPLES WITH DNA

Biological specimen collection: collect 10ml ethylenediaminetetraacetic acid blood samples using a health checkup, then send them to renji sample bank for separation within 2 hours, and store in -80℃ ultra-low temperature refrigerator.

MeSH Terms

Conditions

Cardiovascular Diseases

Study Officials

• Jun Pu, MD,PhD

  RenJi Hospital

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Jun Pu, MD,PhD

CONTACT

86-21-68383477; pujun310@hotmail.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Director of Cardiovascular Medicine

Study Record Dates

• First Submitted: August 16, 2020
• First Posted: August 18, 2020
• Study Start: August 7, 2019
• Primary Completion: December 31, 2025
• Study Completion: December 31, 2025
• Last Updated: July 11, 2023

Record last verified: 2023-07

Locations

CN (1)