Validating the Spanish "Attitudes Toward Genomics and Precision Medicine" (AGPM).

NCT06386861 | Active Not Recruiting

• 1 other identifier: 24.210.01e
• Study Type: interventional
• Target: 851
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators aim to evaluate English and Spanish versions of the "Attitudes toward genomics and precision medicine" instrument (AGPM). This study will help validating a Spanish version of the AGPM among people identifying as Hispanic, Latino, or Latina. Having a valid instrument is important for developing tailored interventions to decrease disparities in genomic healthcare for this population.

Conditions

Adult ALL

Keywords

genomics; precision medicine; attitudes and beliefs; health literacy; health numeracy

Outcome Measures

Primary Outcomes (1)

• Psychometric properties

  Establish the psychometric properties of the translated AGPM

  up to two weeks

Secondary Outcomes (1)

• Health literacy/numeracy

  up to two weeks

Study Arms (2)

AGPM for English Speakers

OTHER

Participants identifying as Hispanic, Latino, or Latina whose primary language is English

Other: Attitudes Toward Genomics and Precision Medicine (English)

AGPM for Spanish Speakers

OTHER

Participants identifying as Hispanic, Latino, or Latina whose primary language is Spanish

Other: Attitudes Toward Genomics and Precision Medicine (Spanish)

Interventions

Attitudes Toward Genomics and Precision Medicine (English) OTHER

completing the English version of the AGPM and validated health literacy and numeracy instruments

AGPM for English Speakers

Attitudes Toward Genomics and Precision Medicine (Spanish) OTHER

completing the Spanish version of the AGPM and validated health literacy and numeracy instruments

AGPM for Spanish Speakers

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• adult (18+ yrs.)
• identifying as Hispanic, Latino, or Latina
• able to provide opt-in electronic informed consent

You may not qualify if:

• under age 18 yrs.
• not identifying as Hispanic, Latino, or Latina
• not able to provide opt-in electronic informed consent

Sponsors & Collaborators

• Boston College: lead

Study Sites (1)

Boston College

Chestnut Hill, Massachusetts, 02467, United States

Location

Related Publications (1)

• DuBois JM, Mozersky J, Antes A, English T, Parsons MV, Baldwin K. Attitudes toward genomics and precision medicine. J Clin Transl Sci. 2021 Apr 8;5(1):e120. doi: 10.1017/cts.2021.774. eCollection 2021.

  PMID: 34267947 BACKGROUND

MeSH Terms

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma; Behavior

Interventions

Precision Medicine

Condition Hierarchy (Ancestors)

Leukemia, Lymphoid; Leukemia; Neoplasms by Histologic Type; Neoplasms; Hematologic Diseases; Hemic and Lymphatic Diseases; Lymphoproliferative Disorders; Lymphatic Diseases; Immunoproliferative Disorders; Immune System Diseases

Intervention Hierarchy (Ancestors)

Therapeutics

Study Officials

• Andrew A Dwyer, PhD

  Boston College

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: 500 English-speaking individuals identifying as Hispanic, Latino, or Latina 500 Spanish-speaking individuals identifying as Hispanic, Latino, or Latina

Study Record Dates

• First Submitted: April 22, 2024
• First Posted: April 26, 2024
• Study Start: April 14, 2024
• Primary Completion: April 15, 2024
• Study Completion: December 31, 2025
• Last Updated: February 5, 2025

Record last verified: 2025-02

Data Sharing

• IPD Sharing: Will share
• Shared Documents: ICF
• Time Frame: Following publication, available indefinitely through the developers of the AGPM
• Access Criteria: Must contact the AGPM developers

Locations

US (1)