NCT06386367

Brief Summary

Malaria is still a leading public health concern in Myanmar. However, people living in rural areas usually showed poor prevention practice despite residing in malaria hotspots. The majority in Myanmar are Buddhists who frequently visit the monastery and receive the speech delivered by the monks. In a malaria high burden township of the Sagaing Region from northern Myanmar, current study will first explore the difference in malaria preventive practices among people residing in different malaria-endemic villages through a mixed-methods approach. Next, this research will address the knowledge gaps by a monastery-based health education delivered by trained Buddhist monks using standardized health messages instruction for six consecutive months between August 2022 to January 2023. To test whether the intervention could balance those gaps among different groups, quantitative data of baseline, 3-month, and 6-month will be compared using descriptive statistics, chi-square test, T-test or repeated ANOVA, and the Difference-In-Differences (DID) analysis, as applicable.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
501

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jul 2022

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2022

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2023

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

March 30, 2024

Completed
24 days until next milestone

First Submitted

Initial submission to the registry

April 23, 2024

Completed
3 days until next milestone

First Posted

Study publicly available on registry

April 26, 2024

Completed
Last Updated

April 29, 2024

Status Verified

April 1, 2024

Enrollment Period

9 months

First QC Date

April 23, 2024

Last Update Submit

April 25, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Malaria knowledge and preventive practices

    To assess pre-existing malaria knowledge and preventive practices among both intervention and control groups, pre-intervention surveys were conducted. Subsequently, three- and six-month post-intervention surveys were conducted to evaluate changes following the intervention. A validated questionnaire translated from English to Burmese was used. The questionnaire comprised three sections: demographic information of the respondents, knowledge of malaria and preventive practices. Each section had multiple small questions, and each correct answer was scored. The resultant scores were aggregated, wherein every participant had the potential to accrue a maximum of ten points pertaining to the attribution of malaria causation, symptoms of malaria, and adoption of personal preventative measures against malaria. The participants were eligible to secure eight points in the domain of malaria diagnosis and treatment, alongside twelve scores for the use of LLINs.

    Pre intervention (July 2022), 3-month post-intervention (Dec 2022) and 6-month post-intervention (Mar 2023)

Study Arms (2)

Monastery-based health education intervention

EXPERIMENTAL

The education sessions were conducted in Burmese by trained monks. They followed the normal teachings of the Buddhist doctrine and typically lasted 30-40 minutes. Our research utilized Burmese as the medium for delivering health messages, and all accompanying materials were meticulously prepared in Burmese. The study team observed at least one to two education sessions in each study village.

Behavioral: Monastery-based health education by Buddhist monks

Control

NO INTERVENTION

Participants in the control group just received routine malaria control services such as diagnostic, treatment and bed net distribution.

Interventions

During the three-month intervention from July to September 2022, a total of 18 health education sessions were conducted across the three intervention villages, with an average of 50 attendees per session, totaling 921 attendees across all sessions.

Monastery-based health education intervention

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • For educational intervention; - voluntary participation
  • For questionnaire surveys;
  • male or female household leaders or immediate family members
  • aged \>18 years who had resided in the study villages for more than one year

You may not qualify if:

  • For questionnaire surveys;
  • \- Individuals who were unable to communicate effectively or were under the influence of narcotics, including alcohol

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Myanmar Health Network Organization

Yangon, 11091, Burma

Location

MeSH Terms

Conditions

Health EducationMalaria

Condition Hierarchy (Ancestors)

Adherence InterventionsMedication AdherencePatient CompliancePatient Acceptance of Health CareTreatment Adherence and ComplianceHealth BehaviorBehaviorProtozoan InfectionsParasitic DiseasesInfectionsMosquito-Borne DiseasesVector Borne Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

April 23, 2024

First Posted

April 26, 2024

Study Start

July 1, 2022

Primary Completion

March 31, 2023

Study Completion

March 30, 2024

Last Updated

April 29, 2024

Record last verified: 2024-04

Locations