Statins Role in Acute Ischemic Stroke
observation
Statins in Acute Ischemic Stroke(Role of Statins in Reperfusion in Acute Stroke )
1 other identifier
observational
105
0 countries
N/A
Brief Summary
Strokes is amajor cause of death and disabilities in different countried
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Aug 2024
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 14, 2024
CompletedFirst Posted
Study publicly available on registry
April 17, 2024
CompletedStudy Start
First participant enrolled
August 13, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 28, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
August 30, 2025
CompletedApril 17, 2024
April 1, 2024
7 months
April 14, 2024
April 14, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
Carotid duplex will be done at the onset and after 1 month and 3 months of the onset.
measure the carotid thickness through Carotid duplex
first day and after 3 mounths
Study Arms (2)
Group ABC
GroupA: recieve rosuvastatin 40mg
Group B
Group B :recive rosuvastatin20
Interventions
Stude include three groupsof people GroupA: recieve rosuvastatin 40mg Group B :recive rosuvastatin 20mg Group C: recive placebo 2- Follow up will be done using NIHSS at the onset and modified Rankin scale at the onset and after 1 month and 3 months of the onset. 3- Carotid duplex will be done at the onset and after 1 month and 3 months of the onset.
Eligibility Criteria
people have acute ischemic stroke
You may qualify if:
- patients.have acute ischemic stroke within 24 hours of onset. 2.patient not received intravenous thrombolysis or mechanical thrombectomy3.patients with no contraindications or hypersensitivity to statins
You may not qualify if:
- \. Patient received IV thrombolysis or underwent mechanical thrombectomy 2. patient have acute ischemic stroke with onset of more than 24 hours 3.patients have hypersestivty or contraindication to statin 4:patients refuse to participate in the study
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Related Publications (1)
Gandhi BS, Kanungo MS. Effect of cortisone on monoamine oxidase of the liver of young & old rats. Indian J Biochem Biophys. 1974 Jun;11(2):102-4. No abstract available.
PMID: 4448456RESULT
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Dr
Study Record Dates
First Submitted
April 14, 2024
First Posted
April 17, 2024
Study Start
August 13, 2024
Primary Completion
February 28, 2025
Study Completion
August 30, 2025
Last Updated
April 17, 2024
Record last verified: 2024-04