Registration of Intravenous Thrombolysis for Acute Ischemic Stroke in Southwestern China（IVTIS）
IVTIS
1 other identifier
observational
3,000
1 country
1
Brief Summary
This study aims to observe the safety and effectiveness of intravenous thrombolysis for acute ischemic stroke in real-world clinical practice.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Nov 2023
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
November 9, 2023
CompletedFirst Posted
Study publicly available on registry
November 14, 2023
CompletedStudy Start
First participant enrolled
November 20, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 15, 2045
ExpectedStudy Completion
Last participant's last visit for all outcomes
May 1, 2046
November 28, 2023
November 1, 2023
22.1 years
November 9, 2023
November 26, 2023
Conditions
Outcome Measures
Primary Outcomes (1)
modified Rankin Scale (mRS) score
Ordinal distribution of mRS at 90±7 days; modified Rankin scale (range, 0 to 6, with a score of 0 indicating no disability, 1 no clinically significant disability, 2 slight disability, 3 moderate disability but remaining able to walk unassisted, 4 moderately severe disability, 5 severe disability, and 6 death)
90±7 days
Secondary Outcomes (11)
Excellent functional outcome
90±7 days
Good functional outcome
90±7 days
mRS 0-3
90±7 days
Change of National Institutes of Health Stroke Scale (NIHSS)
24 hours
Change of National Institutes of Health Stroke Scale (NIHSS)
7 days
- +6 more secondary outcomes
Study Arms (1)
Acute ischemic stroke treated with intravenous thrombolysis
All of acute ischemic stroke patients who treated with intravenous thrombolysis.
Interventions
Intravenous thrombolysis using thrombolytic drugs such as ateplase and teneplase.
Eligibility Criteria
Patients with acute ischemic stroke who received intravenous thrombolysis will be included in the study and no additional exclusion criteria have been set.
You may qualify if:
- The patient was diagnosed with acute ischemic stroke and received intravenous thrombolysis.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Zhengzhou Yuanlead
Study Sites (1)
Affiliated Hospital of Southwest Medical University
Luzhou, 646000, China
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Zhengzhou Yuan
Department of Neurology, Affiliated Hospital of Southwest Medical University, Lu
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Deputy Director of Stroke Center
Study Record Dates
First Submitted
November 9, 2023
First Posted
November 14, 2023
Study Start
November 20, 2023
Primary Completion (Estimated)
December 15, 2045
Study Completion (Estimated)
May 1, 2046
Last Updated
November 28, 2023
Record last verified: 2023-11