NCT06370546

Brief Summary

This study aims to determine the acute effects of high and low-intensity strength training on cardiac autonomic control in hypertensive subjects

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
28

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Mar 2023

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 20, 2023

Completed
1.1 years until next milestone

First Submitted

Initial submission to the registry

April 12, 2024

Completed
5 days until next milestone

First Posted

Study publicly available on registry

April 17, 2024

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 20, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 20, 2024

Completed
Last Updated

September 16, 2025

Status Verified

September 1, 2025

Enrollment Period

1.3 years

First QC Date

April 12, 2024

Last Update Submit

September 9, 2025

Conditions

Physical ExerciseHypertension

Outcome Measures

Primary Outcomes (5)

  • Heart rate variability

    Determine the effects of high and low-intensity strength training on heart rate variability, based on the time between each heartbeat, during the assessment

    2 hours

  • Blood pressure systolic

    Determine the effects of high and low intensity resistance training on blood pressure with a blood pressure monitor for 24 hours.

    24 hours

  • Blood pressure diastolic

    Determine the effects of high and low intensity resistance training on blood pressure diastolic with a blood pressure monitor for 24 hours.

    24 hours

  • Blood pressure mean

    Determine the effects of high and low intensity resistance training on blood pressure mean with a blood pressure monitor for 24 hours.

    24 hours

  • Heart Rate

    Determine the effects of high and low intensity strength training on the behavior of heart rate, using a heart rate monitor, throughout the intervention.

    24 hours

Study Arms (2)

Low Intensity

EXPERIMENTAL

The low-intensity group undergoes a strength training program using barbells, weights and dumbbells, consisting of 6 sets of 12 repetitions each, with an execution speed below 40% of the maximum velocity used in the one-repetition maximum

Other: Low intensity

high intensity

EXPERIMENTAL

The low-intensity group undergoes a strength training program using barbells, weights and dumbbells consisting of 6 sets of 6 repetitions each, with an execution speed equal to or greater than 80% of the maximum velocity used in the one-repetition maximum

Other: high intensity

Interventions

Low intensityOTHER

Low intensity group: participants will be requested to perform the following exercises: 1)squat, 2) rowing, 3)deadlift and 4)bench press. All exercises will be performed with low intensity (40% of the maximum velocity used in one-repetition maximum) and will be supervised by a researcher.

Low Intensity
high intensityOTHER

High intensity group: participants will be requested to perform the following exercises: 1)squat, 2)rowing, 3)deadlift and 4)bench press. All exercises will be performed with high intensity (80% of the maximum velocity used in one-repetition maximum) and will be supervised by a researcher.

high intensity

Eligibility Criteria

Age30 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Participants exclusively diagnosed with hypertension by a medical professional

You may not qualify if:

  • Participants with any other chronic medical condition
  • Subjects with any upper or lower limb injury that prevents strength training
  • Subjects with cardiovascular abnormalities other than hypertension

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Universidad Católica del Maule

Talca, Maule Region, 3469001, Chile

Location

MeSH Terms

Conditions

Motor ActivityHypertension

Interventions

Ultrasonic Waves

Condition Hierarchy (Ancestors)

BehaviorVascular DiseasesCardiovascular Diseases

Intervention Hierarchy (Ancestors)

SoundRadiation, NonionizingRadiationPhysical Phenomena

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Randomized clinical trial, single blinded.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Adjunct Professor

Study Record Dates

First Submitted

April 12, 2024

First Posted

April 17, 2024

Study Start

March 20, 2023

Primary Completion

July 20, 2024

Study Completion

July 20, 2024

Last Updated

September 16, 2025

Record last verified: 2025-09

Locations

CL(1)