Cognitive Functioning in Adults With Somatic Diseases and General Population From a Biopsychosocial Perspective

NCT06365658 | Recruiting

• 1 other identifier: 2024/PTPiP/1
• Study Type: observational
• Target: 600
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this observational study is to investigate cognitive functioning profiles in adults with neurologically recognized aphasic syndromes and general population. The study group consist of minimal 600 adults (over 18 y.o.) who will be examined by qualified diagnosticians. Participants will be evaluated with tasks related to the studied variables: memory, learning and language. Furthermore informations regarding past and present health condition will be collected from participants. The main questions it aims to answer are:

1. 1.What is the profile of memory and learning among polish adults?
2. 2.Do gender and age moderates patterns of memory and learning functioning among polish adults?
3. 3.What is a specific pattern of language functioning in adults with neurologically recognized aphasic syndromes?
4. 4.Do gender moderates specific patterns of language functioning in adults with neurologically recognized aphasic syndromes?
5. 5.general population/control group
6. 6.with neurologically recognized aphasic syndromes
7. 7.seniors (over 60 y.o.)

Conditions

Aphasia; Development, Human; Neuropathology

Keywords

aphasia; memory; learning; language; adults; seniors

Outcome Measures

Primary Outcomes (3)

• Memory and learning

  Test of Memory and Learning (second edition). A standardized test measuring memory functioning and learning abilities. The test includes four basic factors (Verbal Memory, Nonverbal Memory, Complex Memory, and Delayed Recall) and five supplementary factors (Attention/Concentration, Sequential Memory, Free Recall, Associative Recall and Learning). The raw scores obtained in each tested subscale are converted into scores scaled based on age norms, ranging from 1 to 20, where a higher score means better functioning of the examined area, and a lower result means poorer functioning.

  July 3, 2023 until June 30, 2026

• Language

  Boston Diagnostic Aphasia Examination-Third Edition. A spectrum of tools that helps to identify and distinguish among disorders of language function and neurologically recognized aphasic syndromes. The test have five functional subsections: 1) Conversational and Expository Speech, 2) Auditory Comprehension, 3) Oral Expression, 4) Reading and 5) Writing. The raw scores obtained in each tested subscale are converted into a percentile scale, ranging from 1 to 100, where a higher score means better functioning of the examined area, and a lower result means poorer functioning.

  July 3, 2023 until June 30, 2026

• Socio-demographic data

  Author's survey of socio-demographic data, including: gender, month and year of birth, region of residence

  July 3, 2023 until June 30, 2026

Secondary Outcomes (3)

• General mental state

  July 3, 2023 until June 30, 2026

• Health related data

  July 3, 2023 until June 30, 2026

• Education data

  July 3, 2023 until June 30, 2026

Study Arms (3)

General population/control group

Polish adults (age 18 to 60 y.o).

Diagnostic Test: Psychological assessment

Neurologically recognized aphasic syndromes

Polish adults (age 18 to 60 y.o) with neurologically recognized aphasic syndromes.

Diagnostic Test: Psychological assessment

Seniors (over 60 y.o)

Polish adults (over 60 y.o.)

Diagnostic Test: Psychological assessment

Interventions

Psychological assessment DIAGNOSTIC_TEST

Psychological assessment of memory, learning and language

General population/control group; Neurologically recognized aphasic syndromes; Seniors (over 60 y.o)

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Polish adults.

You may qualify if:

• age from 18 to 60 y.o.
• age above 18 y.o.
• neurologically recognized aphasic syndromes
• age above 60 y.o.

You may not qualify if:

• age less then 18 y.o.
• neurologically recognized aphasic syndromes
• age less then 18 y.o.
• no neurologically recognized aphasic syndromes
• age less then 60 y.o.
• diseases of the nervous system, such as: stroke, craniocerebral trauma, neuroinfections, neurodegenerative diseases
• mental disorders such as depression, psychotic disorders, anxiety disorders, addictions

Sponsors & Collaborators

• Bartosz M. Radtke: lead

Study Sites (1)

Laboratory of Psychological and Educational Tests

Gdansk, Pomeranian Voivodeship, 80-239, Poland

RECRUITING

MeSH Terms

Conditions

Aphasia; Language

Condition Hierarchy (Ancestors)

Speech Disorders; Language Disorders; Communication Disorders; Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Communication; Behavior

Study Officials

• Urszula Sajewicz-Radtke, Ph.D.

  Laboratory of Psychological and Educational Tests

  STUDY DIRECTOR

• Bartosz M Radtke, Ph.D.

  Laboratory of Psychological and Educational Tests

  PRINCIPAL INVESTIGATOR

• Ariadna Łada-Maśko, Ph.D.

  Laboratory of Psychological and Educational Tests

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Rafał Nowicki, M.A.

CONTACT

+48509805591; nowicki@pracowniatestow.pl

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: CEO

Study Record Dates

• First Submitted: April 10, 2024
• First Posted: April 15, 2024
• Study Start: July 3, 2023
• Primary Completion (Estimated): June 1, 2026
• Study Completion (Estimated): December 1, 2026
• Last Updated: January 26, 2026

Record last verified: 2026-01

Locations

PL (1)