Comparison of %5 Dextrose and Betamethasone Injections in Patients With Carpal Tunnel Syndrome

NCT06360510 | Completed

• 1 other identifier: 44
• Study Type: observational
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the study is to compare the effectiveness of ultrasound-guided betamethasone and 5% dextrose injection, which is routinely applied in clinical practice, in patients with mild and moderate carpal tunnel syndrome (CTS).

Conditions

Carpal Tunnel Syndrome

Keywords

carpal tunnel syndrome; betamethasone; % 5 dextrose

Outcome Measures

Primary Outcomes (1)

• Numeric rating scale - 10

  The Numeric Rating Scale (NRS) is a simple and widely used tool for assessing pain intensity. Patients are asked to rate their pain on a scale from 0 to 10, where: 0 = No pain 1-3 = Mild pain 4-6 = Moderate pain 7-9 = Severe pain 10 = Worst pain imaginable The patient selects the number that best represents their pain at last one week

  three months

Secondary Outcomes (5)

• boston carpal tunnel syndrome questionnaire

  three months

• median nerve cross sectional area

  three months

• tinnel test positivity

  three months

• phalen test positivity

  three months

• DuruÖz hand index

  three months

Study Arms (2)

%5 dextrose group

Procedure: %5 dextrose injection

betamethasone group

Procedure: betamethasone injection

Interventions

%5 dextrose injection PROCEDURE

hydrodissection with %5 dextrose

%5 dextrose group

betamethasone injection PROCEDURE

perineural betamethasone injection

betamethasone group

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patients that have carpal tunnel syndrome

You may qualify if:

• Paresthesia and pain symptoms in the region corresponding to the distribution of the median nerve
• Detection of mild or moderate CTS by electromyography
• One or both of the Phalen test and/or Tinel sign are positive on physical examination
• Symptoms have persisted for at least 3 months

You may not qualify if:

• Those diagnosed with polyneuropathy, plexopathy, radiculopathy, thoracic outlet syndrome
• Having had surgery or any injection for carpal tunnel syndrome within the last year
• History of wrist fracture
• Those with rheumatoid arthritis, uncontrolled diabetes, gout, chronic renal failure, malignancy, active systemic infection
• Those with cognitive impairment
• Coagulopathy or bleeding tendency
• Pregnancy

Sponsors & Collaborators

• Gaziler Physical Medicine and Rehabilitation Education and Research Hospital: lead

Study Sites (1)

Ankara Gaziler Physical Medicine and Rehabilitation Education and Research Hospital

Ankara, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Carpal Tunnel Syndrome

Interventions

Betamethasone

Condition Hierarchy (Ancestors)

Median Neuropathy; Mononeuropathies; Peripheral Nervous System Diseases; Neuromuscular Diseases; Nervous System Diseases; Nerve Compression Syndromes; Cumulative Trauma Disorders; Sprains and Strains; Wounds and Injuries

Intervention Hierarchy (Ancestors)

Pregnadienetriols; Pregnadienes; Pregnanes; Steroids; Fused-Ring Compounds; Polycyclic Compounds; Steroids, Fluorinated

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Clinical Professor

Study Record Dates

• First Submitted: April 7, 2024
• First Posted: April 11, 2024
• Study Start: May 5, 2023
• Primary Completion: May 5, 2024
• Study Completion: May 5, 2024
• Last Updated: February 23, 2026

Record last verified: 2024-04

Locations

TU (1)