NCT06355440

Brief Summary

The goal of this pilot study is to access the feasibility and impact of a financial navigation program on improving financial toxicity among patients with breast cancer in China. The main questions it aims to answer are:

  • Is the intervention feasible and acceptable among participants?
  • Does the intervention enhance participants' cost-related health literacy?
  • Does the intervention reduce participants' financial toxicity? Researchers will compare the financial navigation program with usual oncology care to preliminarily evaluate its effectiveness. Participants will receive comprehensive information support, including:
  • Strategies on patient-physician costs discussion
  • Skills for inquiring and tracking treatment-related costs
  • Basic knowledge about health insurance
  • Guidance on accessing and applying for financial assistance
  • Suggestions for returning to normal life and work
  • Strategies for holding a financial-related family meeting

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
26

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 18, 2024

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

March 28, 2024

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 28, 2024

Completed
12 days until next milestone

First Posted

Study publicly available on registry

April 9, 2024

Completed
28 days until next milestone

Study Completion

Last participant's last visit for all outcomes

May 7, 2024

Completed
Last Updated

September 25, 2024

Status Verified

June 1, 2024

Enrollment Period

1 month

First QC Date

March 28, 2024

Last Update Submit

September 23, 2024

Conditions

Outcome Measures

Primary Outcomes (6)

  • Eligibility rate

    The eligibility rate will be calculated as the proportion of participants who meet the eligibility criteria among the total number of participants who will be assessed for eligibility. Reasons for participants' ineligibility will be recorded.

    Approximately 1 month

  • Consent rate

    The consent rate will be calculated as the proportion of eligible participants who consent to participate among those who will be approached and eligible for participation. Reasons for participants' refusal to participate will be recorded.

    Approximately 1 month

  • Attrition rate

    The attrition rate will be calculated as the percentage of participants who withdraw from or drop out of the study after enrolment. Reasons for participants' withdrawal or dropout will be recorded.

    Through study completion, an average of 3 month

  • Adherence rate

    The adherence rate will be calculated as the proportion of participants completing the entire program. Reasons for participants' nonadherence to the intervention will be recorded.

    Through study completion, an average of 3 month

  • Patient-reported satisfaction

    Participants' satisfaction will be measured with homemade 5 item questionnaire, with higher scores indicating higher satisfaction.

    1 month after discharge in Financial Navigation Arm

  • Qualitative assessment of the intervention

    Participants' experiences will be captured through one-on-one, semi-structured qualitative interviews.

    1 month after discharge in Financial Navigation Arm

Secondary Outcomes (4)

  • Cost-related health literacy

    Baseline, 1st month since baseline

  • Financial toxicity

    Baseline, 1st month since baseline

  • Material domain of financial toxicity

    1st month since baseline

  • Behavioral domain of financial toxicity

    1st month since baseline

Study Arms (2)

Financial Navigation

EXPERIMENTAL

Participants will receive financial navigation service. During their hospitalization, participants will receive face-to-face information support with material booklets. Following discharge, weekly financial navigation information will be sent via WeChat for 1 month. The financial navigation encompasses comprehensive information support: * Strategies on patient-physician costs discussion * Skills for inquiring and tracking treatment-related costs * Basic knowledge about health insurance * Guidance on accessing and applying for financial assistance * Suggestions for returning to normal life and work * Strategies for holding a financial-related family meeting

Behavioral: Financial Navigation

Usual Care

ACTIVE COMPARATOR

Participants will receive usual care during hospitalization and regular follow-up after discharge. Participants have the freedom to utilize any financial resources, but financial navigators do not offer comprehensive information support. When participants actively inquire about cancer treatment-related costs or financial planning strategies, financial navigators will answer their questions.

Other: Usual Care

Interventions

One-on-one information support with material booklets during hospitalization. Weekly financial navigation information will be sent via WeChat after discharge for 1 month. The financial navigation encompasses comprehensive information support: * Strategies on patient-physician costs discussion * Skills for inquiring and tracking treatment-related costs * Basic knowledge about health insurance * Guidance on accessing and applying for financial assistance * Suggestions for returning to normal life and work * Strategies for holding a financial-related family meeting

Financial Navigation

Participants will receive usual oncology care during hospitalization and regular follow-up after discharge. Participants have the freedom to utilize any financial resources, but financial navigators do not offer comprehensive information support.

Usual Care

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • (1) Newly diagnosed with breast cancer and undergoing surgery during this admission;
  • (2) Female, age 18 years or older;
  • (3) Receiving or expected to receive one or more of the following therapies: chemotherapy, radiotherapy, endocrine therapy, targeted therapy, and immunotherapy;
  • (4) Eastern Cooperative Oncology Group Performance Status 0-2;
  • (5) Provided informed consent to participate in this study.

You may not qualify if:

  • (1) Diagnosed with ductal carcinoma in situ (DCIS)
  • (2) Presence of any serious psychiatric disorders;
  • (3) Cognitive impairments;
  • (4) Difficulty in reading, writing, or communicating in Chinese.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Fudan University Shanghai Cancer Center

Shanghai, Shanghai Municipality, 200032, China

Location

Related Publications (1)

  • Yuan X, Chen L, Sun Y, Kuang Y, Ruan J, Tang L, Qiu J, Xing W. The development and preliminary evaluation of a financial navigation program among patients with breast cancer in China. Asia Pac J Oncol Nurs. 2025 Feb 17;12:100668. doi: 10.1016/j.apjon.2025.100668. eCollection 2025 Dec.

MeSH Terms

Conditions

Financial Stress

Condition Hierarchy (Ancestors)

Stress, PsychologicalBehavioral SymptomsBehavior

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

March 28, 2024

First Posted

April 9, 2024

Study Start

February 18, 2024

Primary Completion

March 28, 2024

Study Completion

May 7, 2024

Last Updated

September 25, 2024

Record last verified: 2024-06

Data Sharing

IPD Sharing
Will not share

We do not plan to share individual participant data due to privacy concerns and confidentiality agreements with participants.

Locations