Uterine Preservation With Acar's Atony Suture for Postpartum Uterine Hemorrhage

NCT06353074 | Completed

• 1 other identifier: 1335cemre.
• Study Type: observational
• Target: 16
• Locations: 1 country
• Sites: 1

Brief Summary

This study is aimed to show effectiveness of a new suture technique to stop postpartum uterine bleeding due to uterine atony.

Conditions

Uterine Atony With Hemorrhage; Postpartum Hemorrhage

Keywords

Cesarean section; compression suture; postpartum hemorrhage

Outcome Measures

Primary Outcomes (1)

• Postpartum hysterectomy and/or intensive care unit need ratio

  The need for hysterectomy or massive transfusion because of unstoppable and mortal bleeding

  Since first operation to discharge from hospital assessed up to 5 days

Study Arms (1)

study group

The patients who had uterine atony during delivery and to whom Acar's atony suture were performed consisted study group.

Eligibility Criteria

• Age: 18 Years - 45 Years
• Sex: female
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

Women admitted to the university hospital for delivery and women referred to the university hospital with uterine atony diagnosis

You may qualify if:

• women without systemic disease

You may not qualify if:

• cardiac disease
• rheumatological disease

Sponsors & Collaborators

• Necmettin Erbakan University: lead

Study Sites (1)

Cemre Alan

Konya, Turkey (Türkiye)

Location

Related Publications (14)

• Say L, Chou D, Gemmill A, Tuncalp O, Moller AB, Daniels J, Gulmezoglu AM, Temmerman M, Alkema L. Global causes of maternal death: a WHO systematic analysis. Lancet Glob Health. 2014 Jun;2(6):e323-33. doi: 10.1016/S2214-109X(14)70227-X. Epub 2014 May 5.

  PMID: 25103301 BACKGROUND

• Santos RR, Martins I, Clode N, Santo S. Uterine preservation with Alcides-Pereira's compressive sutures for postpartum uterine atony. Eur J Obstet Gynecol Reprod Biol. 2022 Oct;277:27-31. doi: 10.1016/j.ejogrb.2022.08.008. Epub 2022 Aug 12.

  PMID: 35987075 BACKGROUND

• Balki M, Wong CA. Refractory uterine atony: still a problem after all these years. Int J Obstet Anesth. 2021 Nov;48:103207. doi: 10.1016/j.ijoa.2021.103207. Epub 2021 Jul 21.

  PMID: 34391025 BACKGROUND

• Bateman BT, Berman MF, Riley LE, Leffert LR. The epidemiology of postpartum hemorrhage in a large, nationwide sample of deliveries. Anesth Analg. 2010 May 1;110(5):1368-73. doi: 10.1213/ANE.0b013e3181d74898. Epub 2010 Mar 17.

  PMID: 20237047 BACKGROUND

• Al-Zirqi I, Vangen S, Forsen L, Stray-Pedersen B. Prevalence and risk factors of severe obstetric haemorrhage. BJOG. 2008 Sep;115(10):1265-72. doi: 10.1111/j.1471-0528.2008.01859.x.

  PMID: 18715412 BACKGROUND

• Ramler PI, van den Akker T, Henriquez DDCA, Zwart JJ, van Roosmalen J, van Lith JMM, van der Bom JG; TeMpOH-1 study group. Women receiving massive transfusion due to postpartum hemorrhage: A comparison over time between two nationwide cohort studies. Acta Obstet Gynecol Scand. 2019 Jun;98(6):795-804. doi: 10.1111/aogs.13542. Epub 2019 Feb 11.

  PMID: 30667050 BACKGROUND

• Huque S, Roberts I, Fawole B, Chaudhri R, Arulkumaran S, Shakur-Still H. Risk factors for peripartum hysterectomy among women with postpartum haemorrhage: analysis of data from the WOMAN trial. BMC Pregnancy Childbirth. 2018 May 29;18(1):186. doi: 10.1186/s12884-018-1829-7.

  PMID: 29843627 BACKGROUND

• B-Lynch C, Coker A, Lawal AH, Abu J, Cowen MJ. The B-Lynch surgical technique for the control of massive postpartum haemorrhage: an alternative to hysterectomy? Five cases reported. Br J Obstet Gynaecol. 1997 Mar;104(3):372-5. doi: 10.1111/j.1471-0528.1997.tb11471.x.

  PMID: 9091019 BACKGROUND

• Nelson WL, O'Brien JM. The uterine sandwich for persistent uterine atony: combining the B-Lynch compression suture and an intrauterine Bakri balloon. Am J Obstet Gynecol. 2007 May;196(5):e9-10. doi: 10.1016/j.ajog.2006.10.887.

  PMID: 17466689 BACKGROUND

• Baskett TF. Uterine compression sutures for postpartum hemorrhage: efficacy, morbidity, and subsequent pregnancy. Obstet Gynecol. 2007 Jul;110(1):68-71. doi: 10.1097/01.AOG.0000267499.40531.a4.

  PMID: 17601898 BACKGROUND

• Acar A, Ercan F, Pekin A, Elci Atilgan A, Sayal HB, Balci O, Gorkemli H. Conservative management of placental invasion anomalies with an intracavitary suture technique. Int J Gynaecol Obstet. 2018 Nov;143(2):184-190. doi: 10.1002/ijgo.12593. Epub 2018 Aug 13.

  PMID: 29989156 BACKGROUND

• Pereira A, Nunes F, Pedroso S, Saraiva J, Retto H, Meirinho M. Compressive uterine sutures to treat postpartum bleeding secondary to uterine atony. Obstet Gynecol. 2005 Sep;106(3):569-72. doi: 10.1097/01.AOG.0000168434.28222.d3.

  PMID: 16135589 BACKGROUND

• Moleiro ML, Braga J, Machado MJ, Guedes-Martins L. Uterine Compression Sutures in Controlling Postpartum Haemorrhage: A Narrative Review. Acta Med Port. 2022 Jan 3;35(1):51-58. doi: 10.20344/amp.11987. Epub 2019 Oct 7.

  PMID: 32208130 BACKGROUND

• Acar A, Alan C, Dogru S. A new technique: Acar's atony suture for postpartum uterine hemorrhage. Z Geburtshilfe Neonatol. 2025 Jun;229(3):195-200. doi: 10.1055/a-2441-6846. Epub 2024 Nov 11.

  PMID: 39529317 DERIVED

MeSH Terms

Conditions

Postpartum Hemorrhage

Condition Hierarchy (Ancestors)

Obstetric Labor Complications; Pregnancy Complications; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Puerperal Disorders; Uterine Hemorrhage; Hemorrhage; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Ali Acar, Clinic Prof.

  Necmettin Erbakan University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Fellow of Gynecologic Oncology

Study Record Dates

• First Submitted: December 26, 2023
• First Posted: April 8, 2024
• Study Start: January 1, 2021
• Primary Completion: November 30, 2023
• Study Completion: November 30, 2023
• Last Updated: April 8, 2024

Record last verified: 2024-04

Locations

TU (1)