Comparison of Analgesic Efficacy in Video-Assisted Thoracoscopic Surgery Patients

NCT06352398 | Completed

• 1 other identifier: BBTuysuz
• Study Type: interventional
• Target: 52
• Locations: 1 country
• Sites: 1

Brief Summary

The 52 patients included in the study were divided into two groups as ESPB (n=26) and SPSIPB (n=26). Before the operation, 0.25% bupivacaine 30 ml was administered to both groups. After admission to the operating room, all patients underwent standard anaesthesia procedures. Morphine 0.05 mg/kg i.v. and parol 1 g i.v. were administered 30 min before the end of the operation. Post operatively the patient was followed up with controlled analgesia. Demographic data, ASA scores, body mass indexes, peri-operative haemodynamic values, remifentanil consumption and duration of surgery were recorded. Post-operative first 24 hours NRS scores, morphine consumption, number of nausea and vomiting episodes were recorded.

Conditions

Video-Assisted Thoracoscopic Surgery

Keywords

Erector spina plan block, postoperative analgesia

Outcome Measures

Primary Outcomes (1)

• morphine consumption first 24 hours

  mg

  up to 24 hours

Secondary Outcomes (1)

• NRS pain score

  up to 24 hours

Study Arms (2)

erector spina plan block (ESPB)

ACTIVE COMPARATOR

erector spina plan block (ESPB) : After providing asepsis and antisepsis conditions to the ESPB group in the sitting position, a high frequency linear USG probe will be placed approximately 2-3 cm lateral to the T5 spinous process in the longitudinal plane. After visualising the T5 transverse process with the in plane approach, the skin will be entered in the craniocaudal direction. Trapezius, rhomboid and erector spinae muscles will be passed and 5 ml of saline will be injected between the erector spinae muscle fascia and vertebral transverse process when the needle rests on the spinous process (approximately 3 cm deep) and the block site will be confirmed. Before the operation 30 ml of 0.25% bupivacaine (1mg/kg) will be injected by negative aspiration.

Procedure: erector spina plan block; Drug: 0.25% bupivacaine

Serratus posterior superior intercostal plan block (SPSIPB)

ACTIVE COMPARATOR

In the SPSIPB group, the patient will be positioned in the lateral position, with the surgical side up and the upper extremity hanging over the patient's head for the USG-guided serratus posterior superior plan block. After asepsis and antisepsis conditions are provided, the spina scapula will be visualised above the scapula with our high frequency linear USG probe. The 3rd rib will be visualised with a high frequency probe medial to the scapula corresponding to the 3rd rib level. The ribs, pleura and the serratus muscle covering it will be determined and the needle tip will be advanced until it touches the 3rd rib.After the 3rd rib is visualised by USG, 5 ml isotonic is given and hydrodissection is performed, 30 ml 0.25% bupivacaine (1mg/kg) will be injected between the serratus posterior superior muscle and the 3rd rib.

Procedure: Serratus posterior superior intercostal plan block (SPSIPB); Drug: 0.25% bupivacaine

Interventions

erector spina plan block PROCEDURE

erector spina plan block

erector spina plan block (ESPB)

Serratus posterior superior intercostal plan block (SPSIPB) PROCEDURE

Serratus posterior superior intercostal plan block (SPSIPB)

Serratus posterior superior intercostal plan block (SPSIPB)

0.25% bupivacaine DRUG

Before the operation, 0.25% bupivacaine 30 ml was administered to both groups.

Serratus posterior superior intercostal plan block (SPSIPB); erector spina plan block (ESPB)

Eligibility Criteria

• Age: 18 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• healthy volunteers with VATS
• ASA 1-2-3
• to 80 years old

You may not qualify if:

• patients with coagulopathy
• wound and infection in the block area
• allergy to local anaesthetic drugs
• mental retardation

Sponsors & Collaborators

• Burcu Bozdogan Tuysuz: lead

Study Sites (1)

Istanbul Medenıyet Unıversıty

Istanbul, Kadıkoy, 34734, Turkey (Türkiye)

Location

Related Publications (1)

• Tulgar S, Ciftci B, Ahiskalioglu A, Bilal B, Sakul BU, Korkmaz AO, Bozkurt NN, De Cassai A, Torres AJ, Elsharkawy H, Alici HA. Serratus Posterior Superior Intercostal Plane Block: A Technical Report on the Description of a Novel Periparavertebral Block for Thoracic Pain. Cureus. 2023 Feb 3;15(2):e34582. doi: 10.7759/cureus.34582. eCollection 2023 Feb.

  PMID: 36883093 BACKGROUND

Related Links

• http

MeSH Terms

Interventions

Bupivacaine

Intervention Hierarchy (Ancestors)

Anilides; Amides; Organic Chemicals; Aniline Compounds; Amines

Study Officials

• burcu bozdogan tuysuz

  medenıyet unıversıty

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: December 21, 2023
• First Posted: April 8, 2024
• Study Start: December 20, 2023
• Primary Completion: February 1, 2024
• Study Completion: April 1, 2024
• Last Updated: April 8, 2024

Record last verified: 2024-04

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)