NCT06350721

Brief Summary

The main goals of this pilot study is to assess the feasibility, usability, satisfaction and safety of the immersive virtual reality system called DizzyVR in participants diagnosed with a vestibular disorder. In addition, it aims to collect preliminary data about clinical effectiveness. The main questions it aims to answer are:

  • To assess the feasibility, usability and safety of the system DizzyVR for the vestibular rehabilitation in participants with vestibular disorders.
  • To detect and record possible adverse events due to the use of DizzyVR.
  • To examine the degree of adherence of the participants to the intervention.
  • To know the average success rate of the different games in each session.
  • To evaluate the average difficulty levels overcome throughout the intervention.
  • To know the usability and satisfaction with the system reported by participants and therapists.
  • To assess preliminary efficacy data on the impact of this new vestibular rehabilitation system on dizziness, gait speed, balance confidence and gait stability. Participants will receive the vestibular rehabilitation based on the novel immersive virtual systema, DizzyVR.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 17, 2024

Completed
3 months until next milestone

First Posted

Study publicly available on registry

April 5, 2024

Completed
6 months until next milestone

Study Start

First participant enrolled

October 1, 2024

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 31, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 31, 2025

Completed
Last Updated

September 25, 2025

Status Verified

September 1, 2025

Enrollment Period

4 months

First QC Date

January 17, 2024

Last Update Submit

September 20, 2025

Conditions

Keywords

Virtual realityVestibularHead Mounted DisplayDizzyVR

Outcome Measures

Primary Outcomes (7)

  • Adherence rate

    percentage of completed sessions

    10 weeks

  • Success rate

    Mean success rates of the games per session

    10 weeks

  • Progression

    Levels of the games accomplished during the sessions.

    10 weeks

  • System Usability Scale (SUS)

    Participants perceived usability of the system.

    10 weeks

  • User Satisfaction Evaluation Questionnaire (USEQ)

    Acceptability of the prototype device/software

    10 weeks

  • Simulator Sickness Questionnaire (SSQ)

    Security of the system

    10 weeks

  • Register of risk and number of adverse events experimented by the stakeholders

    Security of the prototype device

    10 weeks

Secondary Outcomes (4)

  • Dizziness Handicap Inventory

    10 weeks

  • Timed Up and Go Test (TUG)

    10 weeks

  • Activities-specific Balance Confidence Scale (ABC)

    10 weeks

  • Functional Gait Assessment questionnaire (FGA)

    10 weeks

Study Arms (1)

Intervention group

EXPERIMENTAL

Each patient will receive a total of 8 sessions of vestibular rehabilitation with the DizzyVR system. Each session will last for 50 minutes, with a frequency of one session per week. The total duration of the intervention will be 10 weeks, with the initial assessment/T0 taking place in the first week and the final assessment/T2 in the tenth week. Similarly, the total expected participation time for each participant is set at 12 weeks (T3).

Device: DizzyVR

Interventions

DizzyVRDEVICE

Each patient will receive a total of 8 sessions of vestibular rehabilitation with the DizzyVR system. Each session will last for 50 minutes, with a frequency of one session per week. The total duration of the intervention will be 10 weeks, with the initial assessment/T0 taking place in the first week and the final assessment/T2 in the tenth week. Similarly, the total expected participation time for each participant is set at 12 weeks (T3).

Intervention group

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Men or women between the ages of 18 and 75.
  • Confirmed diagnosis of central or peripheral vestibulopathy.
  • Preserved walking ability.
  • Presence of dizziness symptoms as assessed by the Dizziness Handicap Inventory (\> 10 points).

You may not qualify if:

  • Severe visual impairments.
  • Cognitive impairment (Mini Mental State Examination \< 24).
  • Existence of comorbidities severely affecting postural control and balance.
  • Uncontrolled systemic diseases that contradict physical activity.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Universidad de Sevilla

Seville, Spain

Location

MeSH Terms

Conditions

Vestibular Diseases

Condition Hierarchy (Ancestors)

Labyrinth DiseasesEar DiseasesOtorhinolaryngologic Diseases

Study Officials

  • MARIA JESÚS CASUSO-HOLGADO, PhD

    University of Seville

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DEVICE FEASIBILITY
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal investigator

Study Record Dates

First Submitted

January 17, 2024

First Posted

April 5, 2024

Study Start

October 1, 2024

Primary Completion

January 31, 2025

Study Completion

January 31, 2025

Last Updated

September 25, 2025

Record last verified: 2025-09

Data Sharing

IPD Sharing
Will not share

Data of study will be only manage by the researchers of study and the physiotherapist of the clinic

Locations