Using Behavioural and Cultural Insights to Increase Colorectal Cancer Home-testing in Croatia
1 other identifier
interventional
13,000
1 country
1
Brief Summary
Colorectal cancer (CRC) is one of the leading causes of death in Croatia. An average of 3600 cases are diagnosed and an average of 2100 people die from the disease every year. Since 2007, Croatia has invited every man and woman aged 50-74 to participate in the home testing screening programme every two years. Currently only around 36% of the invited request the test-kit and 25% complete the home testing procedure, far below the target of 40-60%. The Croatian Institute of Public Health with technical support from World Health Organization (WHO) Regional Office for Europe is undertaking a mixed-methods research study with the aim to increase the completion of colorectal cancer home testing and improve our knowledge of the barriers and drivers to do so. The study has a quantitative and a qualitative component:
- 1.Quantitative: testing the introduction of a reminder letter to encourage people to respond to the initial invite to participate in the CRC home test program and test which elements of a reminder letter improve response rates.
- 2.Qualitative: conducting in-depth interviews with people from the target population who did or did not respond to the CRC invite letter and reminder to better understand the barriers and drivers to participation.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable colorectal-cancer
Started Mar 2024
Shorter than P25 for not_applicable colorectal-cancer
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 5, 2024
CompletedFirst Submitted
Initial submission to the registry
March 26, 2024
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 1, 2024
CompletedFirst Posted
Study publicly available on registry
April 2, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
July 1, 2024
CompletedApril 2, 2024
March 1, 2024
27 days
March 26, 2024
March 26, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Home test kit ordered
Did the participant order the colorectal cancer home testing kit? Routinely collected data.
5 weeks
Completed colorectal cancer screening
Did the participant complete the home testing kit and return it to the health authority? Routinely collected data.
5 weeks
Secondary Outcomes (2)
Opted out
5 weeks
Qualitative feedback
10 weeks
Study Arms (4)
Control
NO INTERVENTIONParticipants do not receive a reminder letter, which is treatment as usual.
Standard letter
EXPERIMENTALParticipants receive a reminder letter which is based on the current colorectal cancer screening invitation.
Behaviorally informed letter
EXPERIMENTALParticipants receive a reminder letter which incorporates several behavioral components, including an active choice prompt, social norm, simplification, chunking and call to action.
Behaviorally informed letter + testing kit
EXPERIMENTALParticipants receive the behaviorally informed letter plus the colorectal home testing kit, which removes the current barrier of having to request a kit.
Interventions
A reminder letter to encourage recipients to order the colorectal cancer home testing kit, based on the current invite letter.
A reminder letter to encourage recipients to order the colorectal cancer home testing kit, with incorporates severally behaviorally informed components, including an active choice prompt, social norm, call to action, chunking and simplification.
The home testing kit is included with the reminder letter, instead of the usual process of responding to the letter to order the kit
Eligibility Criteria
You may qualify if:
- eligible to participate in the national colorectal cancer screening programme
- live in a study location (Split-Dalmatia or Zagreb City counties)
- did not respond to the cancer screening invite letter
You may not qualify if:
- participated in the colorectal screening programme in the last 24 months
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Veerle Snijderslead
- Croatian Institute of Public Healthcollaborator
- Andrija Štampar School of Public Healthcollaborator
Study Sites (1)
Croatian Institute of Public Health
Zagreb, Croatia
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- SCREENING
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Behavioural Scientist
Study Record Dates
First Submitted
March 26, 2024
First Posted
April 2, 2024
Study Start
March 5, 2024
Primary Completion
April 1, 2024
Study Completion
July 1, 2024
Last Updated
April 2, 2024
Record last verified: 2024-03
Data Sharing
- IPD Sharing
- Will not share
The study utilizes the data that is routinely collected as part the Croatian National Screening Database, only specific approved members of the screening program are able to access and utilize this data. For this reason, it is currently not planned to share individual participant data.