NCT06333028

Brief Summary

A Study to Evaluate the enVista® Aspire (EA) intraocular lens in Subjects Undergoing Cataract Extraction

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
82

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started May 2024

Shorter than P25 for all trials

Geographic Reach
1 country

7 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 20, 2024

Completed
7 days until next milestone

First Posted

Study publicly available on registry

March 27, 2024

Completed
2 months until next milestone

Study Start

First participant enrolled

May 30, 2024

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 13, 2025

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 13, 2025

Completed
Last Updated

May 2, 2025

Status Verified

April 1, 2025

Enrollment Period

10 months

First QC Date

March 20, 2024

Last Update Submit

April 30, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Mean binocular BCDVA (logMAR) at Visit 1

    Mean binocular best-corrected distance visual acuity (BCDVA) (logMAR) at Visit 1. Photopic BCDVA measured at 4 meters.

    Day 60 to Day 270 after second eye implantation

Study Arms (1)

enVista Aspire intraocular lens (IOL)

Subjects bilaterally implanted with enVista Aspire EA IOLs.

Device: enVista Aspire EA IOLs

Interventions

Subjects bilaterally implanted with enVista Aspire EA IOLs

enVista Aspire intraocular lens (IOL)

Eligibility Criteria

Age22 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patient population at study site locations

You may qualify if:

  • Subjects must be 22 years of age or older on the date the Informed Consent Form (ICF) is signed.
  • Subjects with a post operative BCDVA of 20/40 or better.
  • Subjects must have the capability to understand and provide written informed consent on the Institutional Review Board (IRB) approved ICF and authorization as appropriate for local privacy regulations and willing and able to comply with the follow-up study visit.
  • Subjects implanted bilaterally with enVista Aspire EA IOLs, powers ranging from + 6 to + 34.0 D, prior to enrollment into the study on or after 1 November 2023.
  • All subjects with a visually significant PCO (BCDVA worse than 20/40) who undergo a YAG capsulotomy may be enrolled 30 days post YAG procedure and with a postoperative BCDVA 20/40 or better.

You may not qualify if:

  • Subjects with any serious ocular pathology or underlying systemic medical disease (e.g., uncontrolled diabetes) or circumstance that, based on the Investigator's judgment, could confound the results of the study.
  • Subjects for whom a Toric IOL is indicated to achieve emmetropia.
  • Subjects for whom monovision treatment is planned.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (7)

SITE 104

Dover, New Jersey, 07801, United States

Location

Site 105

Woodland Park, New Jersey, 07424, United States

Location

Site 103

Garden City, New York, 11530, United States

Location

Site 107

Cranberry Township, Pennsylvania, 16066, United States

Location

Site 106

Charleston, South Carolina, 29407, United States

Location

Site 101

Sugar Land, Texas, 77478, United States

Location

Site 102

Mount Pleasant, Wisconsin, 53405, United States

Location

MeSH Terms

Conditions

Cataract

Condition Hierarchy (Ancestors)

Lens DiseasesEye Diseases

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 20, 2024

First Posted

March 27, 2024

Study Start

May 30, 2024

Primary Completion

March 13, 2025

Study Completion

March 13, 2025

Last Updated

May 2, 2025

Record last verified: 2025-04

Data Sharing

IPD Sharing
Will not share

Locations