Effect of Jing Si Herbal Tea Liquid Packets on Chronic Pharyngolaryngitis

NCT06331351 | Recruiting

• 1 other identifier: A11203001-1
• Study Type: interventional
• Target: 120
• Locations: 1 country
• Sites: 1

Brief Summary

Chronic pharyngolaryngitis is common and often make people suffer in many aspects. The etiology is numerous, for example, airway hypersensitivity, gastroesophageal acid regurgitation, sicca syndrome, anxiety, etc. The investigators aimed to investigate the effect of Jing Si herbal tea liquid packets on chronic pharyngolaryngitis by a design of randomized, double-blind clinical trial in this study. The subjects who were bed-ridden, without self-care ability, receiving hemodialysis, no idea about the details of this study, poor compliance for this study, alcohol and/or drugs additives, pregnancy and breast-feeding women were excluded from this study. A questionnaire for health and habits was performed at the start of the study, and a questionnaire for Reflux Symptom Index (RSI) was performed at the start and the end of the study. Finally, Student's t-test was used to test the difference between the Jing Si herbal tea group and the control group. And, multivariate linear regression was used to test the violation of clinical factors on the treatment outcome of Jing Si herbal tea liquid packets on chronic pharyngolaryngitis.

Conditions

Chronic Pharyngitis

Keywords

Chronic pharyngitis; Jing Si herbal tea liquid packets; clinical trial

Outcome Measures

Primary Outcomes (2)

• Health questionnaire

  the recording items are as follows: age, gender, height, weight, waist circumference, disease history, smoking or not (quantification), drinking or not (quantification), and eating betel nut or not (quantification) , sleeping status, whether to drink coffee (quantification)

  Before the test begins and after intervention completed (at 1 month)

• Reflux Symptom Index (RSI)

  The Reflux Symptom Index (RSI) is in common use as a semi-quantitative tool to assess symptoms associated with laryngopharyngeal reflux (LPR). RSI is a scoring tool that consists of nine items used to assess various symptoms associated with LPR. Each item has a scale ranging from zero (no complaints) to five (severe complaints), with a maximum of 45 indicating the most severe symptoms.

  Before the test begins and after intervention completed (at 1 month)

Study Arms (2)

control group

PLACEBO COMPARATOR

placebo: 2 times a day, 1 sachet each time.

Other: control group

Jing Si herbal tea liquid packets group

EXPERIMENTAL

Jing Si herbal tea liquid packets: 2 times a day, 1 sachet each time.

Other: Jing Si herbal tea liquid packets

Interventions

control group OTHER

2 times a day, 1 sachet each time.

Also known as: Placebo

control group

Jing Si herbal tea liquid packets OTHER

2 times a day, 1 sachet each time.

Jing Si herbal tea liquid packets group

Eligibility Criteria

• Age: 20 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adult men and women aged 20 to 70 years old.
• Patients with chronic pharyngitis

You may not qualify if:

• Patients who are bedridden or unable to take care of themselves.
• Dialysis patients.
• Patients who cannot understand the details of this study or cannot cooperate with the examination.
• History of alcohol or drug abuse.
• Pregnant and lactating women

Sponsors & Collaborators

• Dalin Tzu Chi General Hospital: lead

Study Sites (1)

Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation

Chiayi City, 66247, Taiwan

RECRUITING

MeSH Terms

Interventions

Control Groups

Intervention Hierarchy (Ancestors)

Epidemiologic Research Design; Epidemiologic Methods; Investigative Techniques; Research Design; Methods

Study Officials

• Juen-Haur Hwang, MD, PhD

  Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation

  STUDY CHAIR

Central Study Contacts

Juen-Haur Hwang, MD, PhD

CONTACT

+886-5-2648000; g120796@tzuchi.com.tw

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, CARE PROVIDER
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 8, 2024
• First Posted: March 26, 2024
• Study Start: February 22, 2024
• Primary Completion (Estimated): October 31, 2026
• Study Completion (Estimated): December 31, 2026
• Last Updated: February 9, 2026

Record last verified: 2026-02

Data Sharing

• IPD Sharing: Will not share

Locations

TW (1)