NCT06330467

Brief Summary

The investigators will study the prevalence of dissociative identity disorder (DID) in three populations at risk in cases of childhood psychotrauma : patients with a diagnosis of borderline personality, patients with a diagnosis of functional dissociative crises (FDC) and patients with early psychosis. The investigators will also study the prevalence of other dissociative disorders and the frequency of complex post-traumatic stress disorder. The investigators will also look for correlations between the type of maltreatment in childhood, the age of onset of trauma and the type of diagnosis of dissociative disorders. The investigators hope to include 150 borderline patients, 150 FDC patients and 50 early psychosis patients. Data collection will be done via a psychometric administration of 7 self-completion questionnaires as well as the completion of the SCID-D semi-structured interview.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
350

participants targeted

Target at P75+ for not_applicable

Timeline
4mo left

Started Jun 2024

Typical duration for not_applicable

Geographic Reach
1 country

3 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress87%
Jun 2024Aug 2026

First Submitted

Initial submission to the registry

March 19, 2024

Completed
7 days until next milestone

First Posted

Study publicly available on registry

March 26, 2024

Completed
2 months until next milestone

Study Start

First participant enrolled

June 4, 2024

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 18, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 18, 2026

Last Updated

April 24, 2026

Status Verified

April 1, 2026

Enrollment Period

2.2 years

First QC Date

March 19, 2024

Last Update Submit

April 21, 2026

Conditions

Keywords

Dissociative Identity Disorder (DID)PsychosisFunctional Dissociative Crises (FDC)Complex PTSDBorderline

Outcome Measures

Primary Outcomes (1)

  • SCID-D : Semi-structured Clinical Interview for diagnosing DSM-5 and ICD-11 Dissociative Disorders / DSM = Diagnostic and Statistical Manual of Mental Disorders / ICD = International Classification of Diseases

    assesses the dissociative identity disorder

    Inclusion visit

Secondary Outcomes (8)

  • SCID-D : Semi-structured Clinical Interview for diagnosing DSM-5 and ICD-11 Dissociative Disorders

    Inclusion visit

  • CTQ-28 : Childhood Trauma Questionnaire

    Inclusion visit

  • life events inventory DSM-5

    Inclusion visit

  • PCL-5 : Posttraumatic stress disorder CheckList-5

    Inclusion visit

  • ITQ : International Trauma Questionnaire

    Inclusion visit

  • +3 more secondary outcomes

Study Arms (3)

Borderline

OTHER

Borderline patients

Diagnostic Test: psychometric assessmentDiagnostic Test: semi-structured clinical interview

Functional Dissociative Crises (FDC)

OTHER

FDC patients

Diagnostic Test: psychometric assessmentDiagnostic Test: semi-structured clinical interview

Early psychosis

OTHER

Early psychosis patients : mental state at risk for psychosis and first psychotic episode

Diagnostic Test: psychometric assessmentDiagnostic Test: semi-structured clinical interview

Interventions

Psychometric testing to assess trauma and dissociative disorders, and in particular dissociative identity disorder.

BorderlineEarly psychosisFunctional Dissociative Crises (FDC)

Semi-structured interview for the assessment of dissociative disorders (SCID-D : Semi-structured Clinical Interview for diagnosing DSM-5 and ICD-11 Dissociative Disorders)

BorderlineEarly psychosisFunctional Dissociative Crises (FDC)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • I-1: For all groups:
  • Male or female
  • Age \> or = 18
  • Enrolled in or benefiting from a social security scheme
  • Patient fluent in French
  • Patient willing to undergo a psychological evaluation between 1h30 and 3h30
  • Patient with a known history of psychotrauma in childhood before the age of 18 (sexual abuse, mistreatment, school harassment, natural disasters, attacks, etc.).
  • Patient having received and understood complete information on the organization of the research and having given written free and informed consent prior to participation in the study.
  • I-2 : Patients in the borderline group
  • Patients with main diagnosis of emotionally labile personality
  • Patients with at least one psychiatric hospitalization in the last 3 years
  • I-3 : Patients in the early psychosis group
  • Patient with a diagnosis of mental state at risk of psychosis according to the criteria defined by CAARMS (Comprehensive Assessment of At Risk Mental State) OR Patients diagnosed with a first psychotic episode on an outpatient basis or following a hospital stay
  • I-4 : Patients in the functional dissociative crises group
  • Patients diagnosed with functional dissociative crises by a specialized epileptologist
  • +10 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Centre Psychothérapique de Nancy - CLIP

Nancy, France

NOT YET RECRUITING

Centre Psychothérapique de Nancy - CMP Jacquard et Des Près

Nancy, France

RECRUITING

CHRU Nancy - Neurology department

Nancy, France

RECRUITING

MeSH Terms

Conditions

Dissociative DisordersDissociative Identity DisorderPsychotic Disorders

Condition Hierarchy (Ancestors)

Mental DisordersSchizophrenia Spectrum and Other Psychotic Disorders

Study Officials

  • Coraline HINGRAY

    Centre Psychothérapique de Nancy

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Tatiana DABROWSKI

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Model Details: 3 groups : borderline, early psychosis and FDC.
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 19, 2024

First Posted

March 26, 2024

Study Start

June 4, 2024

Primary Completion (Estimated)

August 18, 2026

Study Completion (Estimated)

August 18, 2026

Last Updated

April 24, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

Locations