Compensatory and Restorative Rehabilitation Techniques in Stroke

NCT06325085 | Completed DMC

• 1 other identifier: Ayesha Saddiqa
• Study Type: interventional
• Target: 36
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this randomized controlled trial is to find the combined effects of restorative and compensatory cognitive rehabilitation techniques in mild cognitive impairment after stroke.

Conditions

Cognitive Impairment

Keywords

Compensatory rehabilitation; Restorative Rehabilitation; Cognition; Stroke; Executive Functioning

Outcome Measures

Primary Outcomes (2)

• Montreal cognitive assessment test (Urdu version)

  MOCA assesses different cognitive domains: attention and concentration, executive functions, memory, language, visuo-constructional skills, conceptual thinking and orientation. The test is one page,30 point test that can be administered in 10 minutes. MOCA is scored by obtaining an item total and the author recommend a clinical cutoff score of 26.is a Patient-completed, condition-specific functional status questionnaire with 10 items including pain, personal care, lifting, reading, headaches, concentration, work, driving, sleeping and recreation.

  6 weeks

• Cognitive assessment scale for stroke patients (CASP)

  Its a rapid test for screening post stroke cognitive impairment. It can be performed at the patient bedside by a non expert examiner. A CASP score of 35/36 should alert to possible presence of cognitive impairment. Score can help predict medium level cognitive impairment.

  6 weeks

Secondary Outcomes (2)

• Stroke specific quality of life questionnaire (Urdu version)

  6 weeks

• Modified Rankin Scale (MRS)

  6 weeks

Study Arms (2)

Compensatory and restorative rehabilitation techniques

EXPERIMENTAL

compensatory and restorative rehabilitation techniques in stroke patients

Other: compensatory and restorative rehabilitation techniques

Traditional cognitive Rehabilitation training

ACTIVE COMPARATOR

Naming words Counting numbers backwards Spell the word backwards

Other: Traditional cognitive rehabilitation training

Interventions

compensatory and restorative rehabilitation techniques OTHER

compensatory and restorative rehabilitation techniques Frequency: 10 reps 2-3 times/week for 3 consecutive weeks then evaluation of the effects. Continue the same techniques for 3 more weeks and then evaluate the retention effects of restorative and compensatory rehabilitation techniques will be evaluated by 9th week.

Compensatory and restorative rehabilitation techniques

Traditional cognitive rehabilitation training OTHER

Naming words ( ask patient to name food, states, family members) Counting numbers backwards, backward counting of days and months) Spell the word backwards, remembering a piece of information Frequency: 10 reps 2-3 times/week for 3 consecutive weeks then evaluation of the effects. Continue the same techniques for 3 more weeks and then evaluate the retention effects of restorative and compensatory rehabilitation techniques will be evaluated by 9th week.

Traditional cognitive Rehabilitation training

Eligibility Criteria

• Age: 50 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age between 50 and 70 years
• Both Genders
• Individuals diagnosed with stroke 6 months before enrollment
• Minimum 6 years of schooling
• Patients with mild cognitive impairment (score 18-25 on MOCA)
• Individuals able to maintain sitting and standing balance (score 41 on berg balance scale)

You may not qualify if:

• \>10 on post stroke depression rating scale (PSDRS)
• Spasticity (\>3 on Ashworth scale)
• Other psychological disorders
• Patients diagnosed with Alzheimer's and dementia

Sponsors & Collaborators

• Riphah International University: lead

Study Sites (1)

Shafi Hospital Dina

Dina, Punjab Province, Pakistan

Location

MeSH Terms

Conditions

Cognitive Dysfunction; Stroke

Condition Hierarchy (Ancestors)

Cognition Disorders; Neurocognitive Disorders; Mental Disorders; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Aroosa Tariq, MS-NMPT

  Riphah International University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 17, 2024
• First Posted: March 22, 2024
• Study Start: April 16, 2024
• Primary Completion: August 28, 2025
• Study Completion: August 29, 2025
• Last Updated: September 3, 2025

Record last verified: 2025-09

Data Sharing

• IPD Sharing: Will not share

Locations

PA (1)