NCT06324760

Brief Summary

Investigating Tiobec® 400's efficacy in alleviating Restless Legs Syndrome symptoms sheds light on promising therapeutic avenues.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Mar 2020

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 4, 2020

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 2, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 2, 2021

Completed
2.8 years until next milestone

First Submitted

Initial submission to the registry

March 12, 2024

Completed
10 days until next milestone

First Posted

Study publicly available on registry

March 22, 2024

Completed
Last Updated

March 22, 2024

Status Verified

March 1, 2024

Enrollment Period

1.2 years

First QC Date

March 12, 2024

Last Update Submit

March 21, 2024

Conditions

Keywords

RLS

Outcome Measures

Primary Outcomes (1)

  • Measure the subjective RLS symptoms of the participants through the IRLSSG rating scale (IRLS)

    This scale contains 10 items, rated from 0 to 4, according to the severity reported by the patient (0 = none, 1 = mild, 2 = moderate, 3 = severe, 4 = very severe.). The cumulative scores are categorized as mild (1-10), moderate (11-20), severe (21-30), and very severe (31-40).

    6 months

Secondary Outcomes (5)

  • Anthropometric parameters of the patients.

    6 Months

  • Patients' body measurements

    6 Months

  • Measurements of patient anatomy

    6 Months

  • Patients' body characteristics.

    6 Months

  • Measurements of patient anatomy.

    6 Months

Interventions

The investigational product utilized in this research, Tiobec® 400 is a dietary supplement enriched with ALA, B vitamins, and vitamins E and C. T400 is designed to mitigate oxidative stress and support the optimal functioning of the nervous system

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

The data will be collected from patients who meet the selection criteria.

You may qualify if:

  • Participants must be a minimum of 18 years of age.
  • They must have a primary diagnosis of RLS without prior therapeutic interventions for the ailment.
  • They need to provide explicit consent via an informed consent document.

You may not qualify if:

  • Patients diagnosed with pathologies other than RLS that affect sleep quality.
  • Those with persistent renal diseases or any other chronic, severe medical condition.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Medical Center Teknon

Barcelona, 08017, Spain

Location

MeSH Terms

Conditions

Restless Legs Syndrome

Interventions

Vitamin B Complex

Condition Hierarchy (Ancestors)

Nervous System DiseasesSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersParasomniasMental Disorders

Intervention Hierarchy (Ancestors)

VitaminsMicronutrientsPhysiological Effects of DrugsPharmacologic ActionsChemical Actions and Uses

Study Officials

  • Javier Albares, Doctor

    Centro Medico Teknon

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 12, 2024

First Posted

March 22, 2024

Study Start

March 4, 2020

Primary Completion

June 2, 2021

Study Completion

June 2, 2021

Last Updated

March 22, 2024

Record last verified: 2024-03

Locations