Restless Legs Syndrome
182
10
16
129
Key Insights
Highlights
Success Rate
92% trial completion (above average)
Published Results
50 trials with published results (27%)
Research Maturity
129 completed trials (71% of total)
Clinical Risk Assessment
Based on trial outcomes
Moderate Risk
Score: 30/100
6.0%
11 terminated out of 182 trials
92.1%
+5.6% vs benchmark
31%
57 trials in Phase 3/4
39%
50 of 129 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 129 completed trials
Clinical Trials (182)
A Post-Market Study for Long-Term Effectiveness and Safety of the TOMAC System for RLS
Treatment of Restless Leg Syndrome (RLS) Augmentation With Ecopipam, a D1 Specific Antagonist
A Proof of Concept, Phase 2, Double-blind, Randomized Trial With d-Methadone Product Versus Placebo
Treating Leg Symptoms in Women With X-linked Adrenoleukodystrophy
Tonic Motor Activation (TOMAC) Therapy in Patients With Restless Legs Syndrome and Dopaminergic Augmentation
Restless Legs Syndrome in Temporomandibular Joint Disorders
Ecological Momentary Assessment in Patients With Restless Legs Syndrome
Impact of Iron Supplementation Treatment on Brain Iron Concentrations
Analysis of Sympathetic Activity in Willis-Ekbom Disease
Treatment of Restless Legs Symptoms With Pramipexole to Improve the Outcomes of Protracted Opioid Withdrawal in OUD
Functional Connectivity of the Interoceptive Network in RLS
Efficacy of Vibration Therapy on Restless Legs Syndrome and Sleep Disturbances Among Patients Undergoing Hemodialysis
Quality Improvement and Practice Based Research in Neurology Using the EMR
Restless Legs Syndrome and Sleep Quality in Pes Planus
Response to an Investigational Device in Patients With Restless Legs Syndrome
Prevalence and Characteristics of Restless Leg Syndrome in Thai Patients With Parkinson's Disease
Advancing Understanding of Transportation Options
Cranial Electrotherapy for Military Beneficiaries With Restless Legs Syndrome
Restless Leg Syndrome: Is There a Response to Buddhist Walking Meditation in Hemodialysis
Blood Changes After Exercise in Restless Legs Syndrome