NCT06324201

Brief Summary

Observational, multi-center, non-randomized, post-market study. This is a nested sub-study of the REAL AF Registry. Consecutive symptomatic drug refractory paroxysmal atrial fibrillation (PAF) patients from the registry will be screened for enrollment, prospectively or retrospectively, to this sub-study per inclusion and exclusion criteria.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
250

participants targeted

Target at P75+ for all trials

Timeline
22mo left

Started Feb 2024

Longer than P75 for all trials

Geographic Reach
1 country

21 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress55%
Feb 2024Mar 2028

First Submitted

Initial submission to the registry

February 21, 2024

Completed
6 days until next milestone

Study Start

First participant enrolled

February 27, 2024

Completed
23 days until next milestone

First Posted

Study publicly available on registry

March 21, 2024

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2026

Completed
2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2028

Expected
Last Updated

October 31, 2025

Status Verified

October 1, 2025

Enrollment Period

2 years

First QC Date

February 21, 2024

Last Update Submit

October 29, 2025

Conditions

Outcome Measures

Primary Outcomes (4)

  • Safety of the QDOT Micro System use in conjunction with VISITAG SURPOINT Module

    Adverse events from post-procedure through 7-day post ablation visit.

    Day 0-7 post ablation

  • Effectiveness of the QDOT Micro System use in conjunction with VISITAG SURPOINT Module at 12-months.

    Freedom from atrial arrhythmia recurrence at 12 months post procedure.

    12 months

  • Effectiveness of the QDOT Micro System use in conjunction with VISITAG SURPOINT Module at 24-months.

    Freedom from atrial arrhythmia recurrence at 24 months post procedure.

    24 months

  • Effectiveness of the QDOT Micro System use in conjunction with VISITAG SURPOINT Module at 36-months.

    Freedom from atrial arrhythmia recurrence at 36 months post procedure.

    36 months

Interventions

Ablation Procedure for paroxysmal atrial fibrillation

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Study population will consist of patients in the REAL AF registry who have symptomatic PAF and will have, or have undergone, ablation procedures using the QDOT MICRO™ System with VISITAG SURPOINT™ Module

You may qualify if:

  • Symptomatic drug refractory paroxysmal (AF episode terminate spontaneously within 7 days) who, in the opinion of the investigator, are candidates for ablation for AF
  • years of age or older
  • Able and willing to participate in baseline and follow up evaluations for the full length of the sub-study
  • Willing and able to provide informed consent for this sub-study

You may not qualify if:

  • Patients who have undergone catheter ablation for atrial fibrillation (PVI, roof line, posterior wall ablation...)
  • Enrolled in an investigational drug or device clinical trial, or any trial that dictates the treatment plan
  • Persistent or long-standing persistent AF
  • In the opinion of the investigator, any known contraindication to an ablation procedure

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (21)

Arrhythmia Institute at Grandview

Birmingham, Alabama, 35209, United States

RECRUITING

Mobile Cardiology Associates

Mobile, Alabama, 36608, United States

RECRUITING

Community Memorial Health System

Ventura, California, 93003, United States

RECRUITING

Medical City - HCA

Aurora, Colorado, 80012, United States

RECRUITING

Naples Community Hospital

Naples, Florida, 34102, United States

WITHDRAWN

Sarasota Memorial Health

Sarasota, Florida, 34239, United States

RECRUITING

Piedmont Healthcare

Atlanta, Georgia, 30309, United States

RECRUITING

Norton Heart and Vascular Institute

Louisville, Kentucky, 40205, United States

RECRUITING

The Brigham and Womens Hospital

Boston, Massachusetts, 02115, United States

NOT YET RECRUITING

Sparrow Clinical Research Institute

Lansing, Michigan, 48912, United States

RECRUITING

Trinity Health-Michigan Heart

Ypsilanti, Michigan, 48197, United States

RECRUITING

The Christ Hospital

Cincinnati, Ohio, 45219, United States

RECRUITING

University of Cincinnati

Cincinnati, Ohio, 45221, United States

RECRUITING

University of Pennsylvania (UPENN)

Philadelphia, Pennsylvania, 19104, United States

RECRUITING

Allegheny Health

Pittsburgh, Pennsylvania, 15212, United States

RECRUITING

Centra Health, Inc.dba Stroobants Cardiovascular Center

Lynchburg, Virginia, 24501, United States

RECRUITING

Bon Secours Medical Group - Richmond Specialty Care

Richmond, Virginia, 23226, United States

RECRUITING

Valley Health System

Winchester, Virginia, 22601, United States

RECRUITING

Multicare Health Systems-Pulse Heart

Puyallup, Washington, 98372, United States

RECRUITING

Franciscan Heart and Vascular Associates

Tacoma, Washington, 98401, United States

RECRUITING

Mercy Health

Janesville, Wisconsin, 53548, United States

RECRUITING

MeSH Terms

Conditions

Atrial Fibrillation

Condition Hierarchy (Ancestors)

Arrhythmias, CardiacHeart DiseasesCardiovascular DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Brian Sanchez, MD

    J & J Corporation

    STUDY DIRECTOR

Central Study Contacts

Jennifer Moss

CONTACT

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
OTHER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 21, 2024

First Posted

March 21, 2024

Study Start

February 27, 2024

Primary Completion

March 1, 2026

Study Completion (Estimated)

March 1, 2028

Last Updated

October 31, 2025

Record last verified: 2025-10

Data Sharing

IPD Sharing
Will not share

Locations