Motivational, Affective and Performance Effects of Caffeine Supplementation

NCT06321861 | Recruiting

• 1 other identifier: Caffeine_motivation
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

The main objective of the study is to evaluate the influence of caffeine intake on participants' energetic arousal, affect, motivation to achieve a training goal, satisfaction with training, and the sense of agency during training. Consequently, participants will engage in three sessions: caffeine, placebo, and no substance (in counterbalanced order). During each session, their affective and motivational states will be assessed, along with the performance of a standardized physical exercise test. The investigators hypothesize that participants who consume caffeine (caffeine condition) will exhibit higher levels of energy and motivation compared to the other two groups. Additionally, they are expected to experience greater optimism and expectancy regarding their training goals and achieve better results in the physical exercise test. A secondary aim of the study is to examine the impact of genetic variability on motivational and affective states of participants, as well as their performance in the physical exercise test after caffeine. The investigators will assess the CYP1A2 (-163C \> A, rs762551; characterized such as "fast" (AA genotype) and "slow" caffeine metabolizers (C-carriers)) and ADORA2A (1976T \> C; rs5751876; characterized by "high" (TT genotype) or "low" sensitivity to caffeine (C-carriers)).

Conditions

Caffeine; Affect; Goals

Keywords

caffeine; energization; motivation; effort; affect; physical exercise; arousal

Outcome Measures

Primary Outcomes (16)

• Energetic arousal pre-test

  Self-reported energetic arousal contrasting vigour with fatigue, measured with the energetic arousal sub-scale of the University of Wales Institute of Science and Technology Mood Adjective Checklist. The values range from 1-4; higher scores indicate greater energetic arousal.

  Right before the intervention

• Energetic arousal post-test

  Self-reported energetic arousal measured with the energetic arousal sub-scale of the University of Wales Institute of Science and Technology Mood Adjective Checklist. The values range from 1-4; higher scores indicate greater energetic arousal. The change relative to the pre-test will be analyzed.

  60 minutes after taking the capsule (waiting in the no-intervention condition); before training

• Optimism

  Situational optimism (expectancy of positive outcomes) measured with 4 items were participants rate the extent to which they: 1) are positively oriented. 2) are full of optimism. 3) can achieve what I set out to do. 4) are capable of a lot. Responses are given on a 1-7 Likert scale. Higher scores indicate greater optimism. The mean of these items will be computed and the change relative to the pre-test will be analyzed.

  60 minutes after taking the capsule (waiting in the no-intervention condition); before training

• Motivation

  Motivation to accomplish one's training goals measured with a question where participants rate the extent to which they are motivated to achieve the best result in: 1) one-repetition maximum bench press test, 2) bar velocity in the bench press test, 3) strength-endurance test, 4) countermovement jump. Participants respond to each item on a 1-7 Likert scale. Higher scores indicate greater motivation.

  60 minutes after taking the capsule (waiting in the no-intervention condition); before training

• Determination

  Determination to accomplish one's training goals measured with 4 items: 1) During training, everything else will become irrelevant for \[the participant\[. 2) \[The participant\] will put a lot of energy into the training. 3) \[The participant\] will do everything in their power to achieve the training goal. 4) \[The participant\] will reach the training goal even if it requires a great effort. 5) \[The participant\] will train despite fatigue. Participants respond to each item on a 1-7 Likert scale. Higher scores indicate greater determination.

  60 minutes after taking the capsule (waiting in the no-intervention condition); before training

• Relative outcome expectancy

  Expectancy of the training results measured with a question: In relation to participants' typical result, what result do they expect in: 1) one-repetition maximum bench press test, 2) bar velocity in the bench press test, 3) strength-endurance test, 4) countermovement jump. Participants respond to each item on a 1-7 scale anchored 1 = definitely worse than usual and 7 = definitely better than usual. Higher scores indicate more positive outcome expectations.

  60 minutes after taking the capsule (waiting in the no-intervention condition); before training

• Success probability

  Subjective probability of attaining the best result measured with a question: How likely do participants think it is that they will achieve the best result in: 1) one-repetition maximum bench press test, 2) bar velocity in the bench press test, 3) strength-endurance test, 4) countermovement jump. Participants respond to each item on a 1-7 scale anchored 1 = completely unlikely and 7 = certain. Higher scores indicate greater probability of success.

  60 minutes after taking the capsule (waiting in the no-intervention condition); before training

• Prospective effort

  Participants' willingness to invest effort in the training measured with a question: How much effort are participants planning to invest in: 1) one-repetition maximum bench press test, 2) bar velocity in the bench press test, 3) strength-endurance test, 4) countermovement jump. Participants respond on a 0-100% scale. Higher scores indicate greater willingness to invest effort.

  60 minutes after taking the capsule (waiting in the no-intervention condition); before training

• Agency

  Sense of agency measured with two questions: 1) Do participants feel in control over the outcome in..., 2) Do participants feel in control over their performance in... Participants respond to each question in relation to each test outcome: 1) one-repetition maximum bench press test, 2) bar velocity in the bench press test, 3) strength-endurance test, 4) countermovement jump. Responses are given on 1-6 scale anchored 1 = no control and 7 = complete control. Higher scores indicate greater sense of agency.

  60 minutes after taking the capsule (waiting in the no-intervention condition); before training

• Performance in the 1RM test

  Participants' performance in the one-repetition maximum test in bench press \[number of kg\]

  60 minutes after taking the capsule (waiting in the no-intervention condition)

• Performance in the bar velocity in the bench press test

  Participants' performance in the bar velocity during 3 sets of 3 repetitions in the bench press exercise \[m/s\]

  60 minutes after taking the capsule (waiting in the no-intervention condition)

• Performance in the strength-endurance test

  Participants' performance in the strength-endurance test in bench press test (number of repetitions)

  60 minutes after taking the capsule (waiting in the no-intervention condition)

• Performance in the countermovement jump test

  Participants' performance in the countermovement jump test (number of cm)

  60 minutes after taking the capsule (waiting in the no-intervention condition)

• Satisfaction with the results

  Participants' satisfaction with their training results measured with a question: How satisfied are participants with their results in: 1) one-repetition maximum bench press test, 2) bar velocity in the bench press test, 3) strength-endurance test, 4) countermovement jump. Participants respond to each item on a 1-7 scale anchored 1 = definitely unsatisfied to 7 = definitely satisfied. Higher scores indicate greater satisfaction with the results.

  Immediately after the physical exercise test

• Retrospective effort

  Participants' assessment of effort invested in the training measured with a question: How much effort did participants invest in:1) one-repetition maximum bench press test, 2) bar velocity in the bench press test, 3) strength-endurance test, 4) countermovement jump. Participants respond on a 0-100% scale. Higher scores indicate greater effort.

  Immediately after the physical exercise test

• Retrospective agency

  Sense of agency measured with two questions: 1) Did participants feel in control over the outcome in..., 2) Did participants feel in control over their performance in... Participants respond to each question in relation to each test outcome: 1) one-repetition maximum bench press test, 2) bar velocity in the bench press test, 3) strength-endurance test, 4) countermovement jump. Responses are given on 1-6 scale anchored 1 = no control and 7 = complete control. Higher scores indicate greater sense of agency.

  Immediately after the physical exercise test

Secondary Outcomes (11)

• Goal importance

  60 minutes after taking the capsule (waiting in the no-intervention condition); before training

• Prospective difficulty

  60 minutes after taking the capsule (waiting in the no-intervention condition); before training

• Expected performance in the 1RM test

  60 minutes after taking the capsule (waiting in the no-intervention condition); before training

• Expected performance in the bar velocity in the bench press test

  60 minutes after taking the capsule (waiting in the no-intervention condition); before training

• Expected performance in the strength-endurance test

  60 minutes after taking the capsule (waiting in the no-intervention condition); before training

Study Arms (3)

Caffeine

EXPERIMENTAL

Participants will take a caffeine pill (3mg/kg of body mass) 60 minutes before the physical exercise test.

Dietary Supplement: Caffeine

Placebo

PLACEBO COMPARATOR

Participants will take a placebo pill 60 minutes before the physical exercise test.

Dietary Supplement: Placebo

No substance

OTHER

Participants receive no pills in this condition before the physical exercise test.

Other: No substance

Interventions

Caffeine DIETARY_SUPPLEMENT

Participants will take one caffeine pill. The dose of caffeine will be calculated based on participants' body mass (3mg/kg body mass). Caffeine will be provided in capsules containing the individual amount of caffeine and will be administered orally 60 min before the onset of the exercise protocol.

Caffeine

Placebo DIETARY_SUPPLEMENT

Participants will take one pill with no caffeine in it. The manufacturer of the caffeine capsules will also prepare identical placebo capsules filled out with a microcrystalline cellulose. Placebo will be administered orally 60 min before the onset of the exercise protocol.

Placebo

No substance OTHER

Participants will take no substance. They will just wait 60 minutes and then engage in the exercise protocol.

No substance

Eligibility Criteria

• Age: 18 Years - 30 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Age 18-30 years
• Caffeine consumption
• Engagement in physical activity.

You may not qualify if:

• Diagnosed cardiovascular, metabolic, gastrointestinal, or neurological diseases
• Taking medications or supplements that may affect test results
• Tobacco smoking
• Pregnancy
• Potential allergy to caffeine.

Sponsors & Collaborators

• Jagiellonian University: lead
• The Jerzy Kukuczka Academy of Physical Education in Katowice: collaborator
• University School of Physical Education, Krakow, Poland: collaborator

Study Sites (1)

The Jerzy Kukuczka Academy of Physical Education in Katowice

Katowice, Poland

RECRUITING

Related Publications (2)

• Matthews G; Jones DM, Chamberlain AG. Refining the measurement of mood: The UWIST mood adjective checklist. British Journal of Psychology, 1990, 81(1): 17-42.

  BACKGROUND

• Szumowska E, Molinario E, Jaśko K, Hudiyana J, Firdiani NF, Penrod J, Jaume LC, Leander NP, Kreienkamp J, Agostini M, Gruszka A, Szumska I, Stelmaszyńska D, Gola M, Altungy P, Gómez Á, Cacek J, & Kruglanski AW (2023). The Extreme Personality: Individual Differences in Proneness to Motivational Imbalance. Manuscript submitted for publication.

  BACKGROUND

MeSH Terms

Conditions

Motor Activity

Interventions

Caffeine

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Xanthines; Alkaloids; Heterocyclic Compounds; Purinones; Purines; Heterocyclic Compounds, 2-Ring; Heterocyclic Compounds, Fused-Ring

Study Officials

• Ewa Szumowska

  Jagiellonian University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Ewa Szumowska

CONTACT

+48504756394; ewa.szumowska@uj.edu.pl

Aleksandra Filip-Stachnik

CONTACT

a.filip@awf.katowice.pl

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: BASIC SCIENCE
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant

Model Details: Each participant will take part in three similar sessions differing by the substance they receive: caffeine (intervention group), placebo, no substance. Sessions will be about one week apart.

Study Record Dates

• First Submitted: January 17, 2024
• First Posted: March 20, 2024
• Study Start: January 19, 2024
• Primary Completion: May 1, 2024
• Study Completion: May 1, 2024
• Last Updated: March 20, 2024

Record last verified: 2024-03

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, ICF, ANALYTIC CODE
• Time Frame: The data will become available after preparing the article summarizing the study results. The data will be shared for at least 5 years.
• Access Criteria: All researchers possessing the link to the data will be able to access it.

Locations

PL (1)