Effectiveness of Neuroscience-based Pain Education in Patients With Chronic Neck Pain

NCT06320938 | Completed

• 1 other identifier: 2024/18
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The effectiveness of neuroscience-based pain education, myofascial induction technique, and home exercise programs will be compared in patients with chronic neck pain.

Conditions

Cervical Spine Disease

Keywords

Pain neuroscience education; Myofascial induction technique; Myofascial treatment; Home exercises; Pain; Neck Disability

Outcome Measures

Primary Outcomes (8)

• Short Form McGill Pain Questionnaire

  A short form of the McGill Pain Questionnaire (SF-MPQ) used in pain assessment consists of four sections. In the first section, participants are asked to mark the location of pain on a body diagram. In the second section, participants are asked to select the word that best describes their pain from twenty subgroups. The third section investigates the relationship of pain over time, while the fourth and final section requires participants to indicate the intensity of pain on a scale of 1 to 5 and provide written responses to six questions. The questionnaire is scored from 0 to 112. The higher the pain score, the greater the pain.

  Baseline,8 weeks, 6 months

• Algometric Digital Measurement

  It is a digital device used to evaluate trigger point sensitivity.

  Baseline,8 weeks, 6 months

• Central Sensitization Inventory

  The scale, which can be applied in chronic pain, is used in central sensitization syndromes. It consists of two parts. Section A questions health-related symptoms, and part B questions whether any central sensitization syndromes have been diagnosed before.

  Baseline,8 weeks, 6 months

• Head Posture Evaluation

  Forward head posture is measured with a goniometer, which measures the angle between the horizontal plane and the seventh cervical vertebra and ear line.

  Baseline,8 weeks, 6 months

• Neck Disability Index

  The scale consists of ten headings in total. It includes neck pain intensity, personal care, lifting, reading, headaches, concentration, driving, sleep, and leisure activities.

  Baseline,8 weeks, 6 months

• Pittsburgh Sleep Quality Index

  This survey contains 24 questions about sleep status, both during the day and at night. Nineteen of these are to be answered personally, and five are to be answered by a spouse or roommate.

  Baseline,8 weeks, 6 months

• 36-Item Short Form Health Survey Questionnaire

  36-Item Short Form Health Survey (SF-36) questionnaire consists of eight subscales: physical functioning, social functioning, role limitations due to physical problems, pain, vitality, mental health, and general health perception. Each subscale is scored from 0 to 100, and the scores from these subscales are not summed. A high score indicates good health status.

  Baseline,8 weeks, 6 months

• Pain Catastrophizing Scale

  The Pain Catastrophizing Scale (PCS) is a 13-item self-report measure of catastrophizing in the context of actual or anticipated pain. The PCS measures catastrophizing as a multidimensional construct with three subscales: rumination, magnification, and helplessness. Rumination focuses on thoughts related to pain, helplessness reflects feelings of helplessness in coping with a painful situation, and magnification is a general view of the threat of pain. High PCS scores are associated with greater pain and more functional impairment. A total score above 30 represents clinically significant levels of pain catastrophizing.

  Baseline,8 weeks, 6 months

Study Arms (3)

Neuroscience-Based Pain Education Combined with Home Exercise Program

ACTIVE COMPARATOR

Patients in this group will receive Neuroscience-Based Pain Education (NPE) treatment in addition to the home exercise program. Training sessions are planned once a week for an average of 35-45 minutes and 8 sessions. NPE will be performed by a physiotherapist who has an internationally recognized certificate in this regard. Training sessions will be organized as one-on-one conversation sessions focusing on the neurophysiology of pain, and patients will be reinforced through PowerPoint presentations and visual pictures, templates, and metaphors.

Other: Neuroscience-Based Pain Education Combined with Home Exercise Program

Myofascial Induction Techniques Combined with Home Exercise Program

ACTIVE COMPARATOR

In addition to the home exercise program, Myofascial Induction Techniques (MIT) group patients will have MIT applied to the cervical and upper thoracic regions by a physiotherapist trained and experienced in myofascial treatments. The application will be once a week for 8 weeks, with an average duration of 35-45 minutes.

Other: Myofascial Induction Techniques Combined with Home Exercise Program

Home Exercise Program

ACTIVE COMPARATOR

Patients in this group will be taught an exercise program after undergoing general training. Exercises will include stretching and strengthening exercises for neck muscles and posture exercises. Patients are asked to take 35-45 minutes once a day, five days a week, for 8 weeks. They will be asked to do the given home exercises and fill out follow-up charts. The continuity of the exercises will be ensured by sending reminder messages to this group of patients once a week by the physiotherapist about doing their exercises.

Other: Home Exercises Group

Interventions

Neuroscience-Based Pain Education Combined with Home Exercise Program OTHER

Neuroscience-Based Pain Education and Home Exercises will be applied.

Neuroscience-Based Pain Education Combined with Home Exercise Program

Myofascial Induction Techniques Combined with Home Exercise Program OTHER

Myofascial Induction Techniques and Home Exercises will be applied.

Myofascial Induction Techniques Combined with Home Exercise Program

Home Exercises Group OTHER

Home Exercises wiil be applied

Home Exercise Program

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Ages between 18-60 years old,
• Patients with non-specific neck pain for at least 3 months,
• Having pain severity of four or more according to the Visual analogue scale (VAS),
• Patients with Pain Catastrophizing Scale score \> 30
• Patients with a Central Sensitization Inventory score \> 30
• Not having received physiotherapy and manual therapy within the last 3 months,
• Those who have not received and will not receive medical treatment in the last 3 months.

You may not qualify if:

• Having a history of neck and spine surgery,
• Patients with whiplash injury, fracture history,
• Having unstable neurological findings,
• Presence of a pathology such as hernia and root compression in the cervical region,
• Those who regularly use analgesic and anti-inflammatory drugs,
• A communication problem may prevent the implementation of the evaluations or treatment program.

Sponsors & Collaborators

• Turkoglu Dr. Kemal Beyazit State Hospital: lead

Study Sites (1)

Türkoğlu Dr. Kemal Beyazıt State Hospital

Kahramanmaraş, Turkey (Türkiye)

Location

Related Publications (3)

• Bernetti A, Agostini F, de Sire A, Mangone M, Tognolo L, Di Cesare A, Ruiu P, Paolucci T, Invernizzi M, Paoloni M. Neuropathic Pain and Rehabilitation: A Systematic Review of International Guidelines. Diagnostics (Basel). 2021 Jan 5;11(1):74. doi: 10.3390/diagnostics11010074.

  PMID: 33466426 BACKGROUND

• Cohen SP, Vase L, Hooten WM. Chronic pain: an update on burden, best practices, and new advances. Lancet. 2021 May 29;397(10289):2082-2097. doi: 10.1016/S0140-6736(21)00393-7.

  PMID: 34062143 BACKGROUND

• Javdaneh N, Saeterbakken AH, Shams A, Barati AH. Pain Neuroscience Education Combined with Therapeutic Exercises Provides Added Benefit in the Treatment of Chronic Neck Pain. Int J Environ Res Public Health. 2021 Aug 22;18(16):8848. doi: 10.3390/ijerph18168848.

  PMID: 34444594 BACKGROUND

MeSH Terms

Conditions

Pain

Condition Hierarchy (Ancestors)

Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Aysenur Tuncer, Assoc. Prof.

  Hasan Kalyoncu University

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: March 13, 2024
• First Posted: March 20, 2024
• Study Start: April 18, 2024
• Primary Completion: January 15, 2025
• Study Completion: May 25, 2025
• Last Updated: September 3, 2025

Record last verified: 2024-08

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)