Intervention on Non-prescription Antibiotic Use Among the Public

NCT06317415 | Completed

• 1 other identifier: HuazhongU20240312
• Study Type: interventional
• Target: 1,550
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to test the effectiveness of health education int led by community health workers for non-prescription antibiotic use among the public. In this two arm cluster randomised trial, In this two-arm cluster randomized controlled trial, 22 communities were randomly allocated in a 1:1 ratio to intervention and control groups. In the intervention group, family doctors will conduct WeChat-based health education on responsible use of antibiotic for the participants. In the control group, only routine public health education will be provided without any involvement in antibiotic use. The primary outcome is the incidence of antibiotic use without prescription in the past month.

Conditions

Non-Prescription Drug Misuse; Antibiotic Use

Keywords

Cluster randomized trial; Non-prescription; antibiotic

Outcome Measures

Primary Outcomes (1)

• Rate of non-prescription antibiotic use among the public

  Rate of Antibiotic use without prescription in the past month measured by self-designed questionnaire。

  within one month

Study Arms (2)

Intervention group

EXPERIMENTAL

Behavioral: WeChat-based health education on antibiotic use

control group

PLACEBO COMPARATOR

Behavioral: Regular public health education

Interventions

WeChat-based health education on antibiotic use BEHAVIORAL

Health education based on the WeChat platform includes popular science articles on WeChat public Platform and health education videos.

Intervention group

Regular public health education BEHAVIORAL

Health education information on the prevention and control of common chronic diseases

control group

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Aged between 18 and 75 years old;
• Local residents (residing for more than 6 months) with no plans for employment, study, or relocation in the next six months;
• Having normal cognitive, comprehension, and independent communication abilities, and voluntarily participating in this study;
• Able to use WeChat independently or with guidance from family members.

You may not qualify if:

• Unable to comprehend the purpose of the survey, unwilling to cooperate, or lacking willingness to provide honest answers to questions;
• Illiterate, severely physically disabled, or lacking necessary comprehension abilities;
• Healthcare professionals, such as doctors, nurses, pharmacists, etc.;
• Individuals with autoimmune diseases or hereditary diseases affecting the use of common medications;

Sponsors & Collaborators

• Huazhong University of Science and Technology: lead
• Fuyong People's Hospital, Bao 'an District, Shenzhen City, Guangdong: collaborator

Study Sites (1)

Fuyong People's Hospital

Shenzhen, Guangdong, 518103, China

Location

MeSH Terms

Conditions

Drug Misuse

Condition Hierarchy (Ancestors)

Substance-Related Disorders; Chemically-Induced Disorders; Mental Disorders

Study Officials

• Xiaoxv Yin

  Huazhong University of Science and Technology

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: March 12, 2024
• First Posted: March 19, 2024
• Study Start: April 1, 2023
• Primary Completion: December 31, 2023
• Study Completion: March 1, 2024
• Last Updated: March 20, 2024

Record last verified: 2024-03

Locations

CN (1)